PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30068325-11 2018 Further in vitro studies showed that 1) silica-induced HO-1 was significantly attenuated by inhibiting ERK activation, and 2) carbon monoxide and bilirubin as final byproducts of HO-1 could inhibit ERK activation. Carbon Monoxide 126-141 mitogen-activated protein kinase 1 Mus musculus 198-201 30068325-12 2018 Taken together, silica-induced HO-1 upregulation was mediated by ERK activation, and HO-1 further regulates ERK activation via its final byproducts, carbon monoxide and bilirubin. Carbon Monoxide 149-164 mitogen-activated protein kinase 1 Mus musculus 108-111 23994557-0 2013 Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway. Carbon Monoxide 0-15 mitogen-activated protein kinase 1 Mus musculus 107-111