PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26523625-14	2016	CONCLUSION: In children, metastatic PHEOs/PGLs are mainly due to SDHB mutations; in adults they are equally distributed between in SDHB mutations and AST, with better 5- and 10-year survival rates for ASTs.	pheos	36-41	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	65-69	
27838885-4	2017	In addition, both adrenal glands were found to have diffuse or nodular adrenal medullary hyperplasia (AMH), a histopathological feature previously described as a precursor of MEN2- and SDHB-related PHEOs but not MAX.	pheos	198-203	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	185-189	
25873086-4	2015	EXPERIMENTAL DESIGN: [(68)Ga]-DOTATATE PET/CT was prospectively performed in 17 patients with SDHB-related metastatic PHEOs/PGLs.	pheos	118-123	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	94-98	
23322515-3	2013	In particular, malignant PHEOs/PGLs, more specifically the tumors that result from mutations in succinate dehydrogenase subunit B (SDHB), are a clear concern, and novel therapies should be developed to address this problem.	pheos	25-30	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	96-129	
25048685-3	2014	This study evaluated the size and age at diagnosis of primary SDHB-related PHEOs/PGLs as independent predictors of their metastatic behavior and outcome (survival).	pheos	75-80	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	62-66	
23322515-3	2013	In particular, malignant PHEOs/PGLs, more specifically the tumors that result from mutations in succinate dehydrogenase subunit B (SDHB), are a clear concern, and novel therapies should be developed to address this problem.	pheos	25-30	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	131-135	
22859959-3	2012	To date, the molecular mechanisms causing the more aggressive phenotype in SDHB-PHEOs/PGLs remain largely unknown.	pheos	80-85	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	75-79	
22859959-10	2012	Although there was no direct evidence for increased reactive oxygen species production, elevated superoxide dismutase 2 expression may reflect elevated oxidative stress in SDHB-derived PHEOs/PGLs.	pheos	185-190	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	172-176	
22859959-12	2012	In addition, we present evidence for increased LDHA and SOD2 expression in SDHB-PHEOs/PGLs, proteins that have been proposed as promising therapeutic targets in other cancers.	pheos	80-85	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	75-79	
19570738-9	2009	The so called "flip-flop" imaging showing superiority of non-specific [18F] flurodeoxyglucose (FDG) PET over specific [18F]DA PET has been described in rapidly progressive, often metastatic SDHB-associated PHEOs.	pheos	206-211	succinate dehydrogenase complex iron sulfur subunit B	Homo sapiens	190-194