PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35007726-3	2022	Therefore, a new class of boronic acid derivate was developed to elucidate the possible mechanistic link between PKM2 activation and TPI1 activity, which has a significant role in the redox balance in cancer.	Boronic Acids	26-38	pyruvate kinase M1/2	Homo sapiens	113-117	
35007726-4	2022	The present in vitro study revealed that treatment with boronic acid-based compound 1 and DASA-58 was found to activate PKM2 with an AC50 of 25 nM and 52 nM, respectively.	Boronic Acids	56-68	pyruvate kinase M1/2	Homo sapiens	120-124	
33901643-0	2021	Discovery of boronic acid-based potent activators of tumor pyruvate kinase M2 and development of gastroretentive nanoformulation for oral dosing.	Boronic Acids	13-25	pyruvate kinase M1/2	Homo sapiens	59-77	
33901643-3	2021	Herein, we describe the design, synthesis, and development of boronic acid-based molecules as activators of PKM2.	Boronic Acids	62-74	pyruvate kinase M1/2	Homo sapiens	108-112