PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27368987-4 2016 The present study aimed to evaluate the efficacy of the modified Hodge test (MHT) and a boronic acid-based combined disk test using carbapenems as substrates for the phenotypic determination of OXA-48 and NDM type carbapenemases in 45 epidemiologically unrelated carbapenem-resistant clinical isolates of Klebsiella pneumoniae (13 isolates), Acinetobacter baumanii (20 isolates), and Pseudomonas aeruginosa (12 isolates). Boronic Acids 88-100 OXA-48 Klebsiella pneumoniae 194-200 27368987-5 2016 RESULTS: Boronic acid disk test using meropenem as substrate and 600 microg of 3- aminophenylboronic acid (APB) was the most sensitive method (83.33 %) for detection of OXA-48, while the most specific method was MHT (100 %). Boronic Acids 9-21 OXA-48 Klebsiella pneumoniae 169-175 27368987-7 2016 CONCLUSIONS: The results of the present study indicate that phenotypic screening with the MHT and the boronic acid disk test may be used to detect OXA-48 and NDM carbapenemases in Gram-negative bacilli clinical isolates, and that these tests can be easily applied in tertiary care settings with minimal infrastructure. Boronic Acids 102-114 OXA-48 Klebsiella pneumoniae 147-153