PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35164361-1 2022 A family of novel efficient non-oxime compounds exhibited promising reactivation efficacy for VX and sarin inhibited human acetylcholinesterase was discovered. Sarin 101-106 acetylcholinesterase (Cartwright blood group) Homo sapiens 123-143 35526478-4 2022 Mono-fluorinated oximes showed comparable reactivation to non-halogenated (except asoxime) and mono-chlorinated oximes in case of AChE inhibited by sarin, cyclosarin, VX, and tabun, but were less efficient than di-chlorinated ones. Sarin 148-153 acetylcholinesterase (Cartwright blood group) Homo sapiens 130-134 33538594-5 2021 To gain insight into this issue, the structures of hAChE inhibited by tabun, sarin, cyclosarin, soman, and GP were obtained along with the inhibition kinetics for these agents. Sarin 77-82 acetylcholinesterase (Cartwright blood group) Homo sapiens 51-56 3699334-1 1986 The kinetics of the reactivation of acetylcholinesterase inhibited by isopropyl methylphosphonofluoridate was studied. Sarin 70-105 acetylcholinesterase (Cartwright blood group) Homo sapiens 36-56 5507658-0 1970 Dephosphorylation in vivo of brain acetylcholinesterase inhibited by isopropyl methylphosphonofluoridate (Sarin). Sarin 69-104 acetylcholinesterase (Cartwright blood group) Homo sapiens 35-55 32583098-3 2020 The reactivation was notable for both AChE and BChE inhibited by VX, cyclosarin, sarin and paraoxon, if quinuclidinium compounds contained the benzyl group attached to the quinuclidinium moiety. Sarin 74-79 acetylcholinesterase (Cartwright blood group) Homo sapiens 38-42 22768972-3 2012 AChE is a target of several toxins such as insecticide carbofuran, nerve agents, sarin, soman, tabun and VX. Sarin 81-86 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 22975155-1 2013 A library of more than 200 novel uncharged oxime reactivators was used to select and refine lead reactivators of human acetylcholinesterase (hAChE) covalently conjugated with sarin, cyclosarin, VX, paraoxon and tabun. Sarin 175-180 acetylcholinesterase (Cartwright blood group) Homo sapiens 141-146 32454005-5 2020 All compounds were assessed for their ability to reactivate human acetylcholinesterase inhibited by the nerve agents VX, tabun, sarin, cyclosarin and paraoxon in vitro. Sarin 128-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 66-86 32388435-4 2020 It was also found that some non-oxime derivatives of Mannich phenols displayed obvious reactivation potency for VX, sarin and pesticides inhibited hAChE even in very low concentration. Sarin 116-121 acetylcholinesterase (Cartwright blood group) Homo sapiens 147-152 27705071-1 2016 Sarin (GB, O-isopropyl methylphosphonofluoridate) is a potent organophosphorus (OP) nerve agent that inhibits acetylcholinesterase (AChE) irreversibly. Sarin 0-5 acetylcholinesterase (Cartwright blood group) Homo sapiens 110-130 27705071-1 2016 Sarin (GB, O-isopropyl methylphosphonofluoridate) is a potent organophosphorus (OP) nerve agent that inhibits acetylcholinesterase (AChE) irreversibly. Sarin 0-5 acetylcholinesterase (Cartwright blood group) Homo sapiens 132-136 27705071-1 2016 Sarin (GB, O-isopropyl methylphosphonofluoridate) is a potent organophosphorus (OP) nerve agent that inhibits acetylcholinesterase (AChE) irreversibly. Sarin 11-48 acetylcholinesterase (Cartwright blood group) Homo sapiens 110-130 27705071-1 2016 Sarin (GB, O-isopropyl methylphosphonofluoridate) is a potent organophosphorus (OP) nerve agent that inhibits acetylcholinesterase (AChE) irreversibly. Sarin 11-48 acetylcholinesterase (Cartwright blood group) Homo sapiens 132-136 15095579-0 2004 [In vitro reactivation of acetylcholinesterase inhibition by O-isopropylmethylfluorophosphonate using the bisquarternary oxime, HS-6]. Sarin 61-95 acetylcholinesterase (Cartwright blood group) Homo sapiens 26-46 19536291-1 2009 Organophosphonates such as isopropyl metylphosphonofluoridate (sarin) are extremely toxic as they phosphonylate the catalytic serine residue of acetylcholinesterase (AChE), an enzyme essential to humans and other species. Sarin 63-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 144-164 19536291-1 2009 Organophosphonates such as isopropyl metylphosphonofluoridate (sarin) are extremely toxic as they phosphonylate the catalytic serine residue of acetylcholinesterase (AChE), an enzyme essential to humans and other species. Sarin 63-68 acetylcholinesterase (Cartwright blood group) Homo sapiens 166-170 17096183-0 2006 New safe method for preparation of sarin-exposed human erythrocytes acetylcholinesterase using non-toxic and stable sarin analogue isopropyl p-nitrophenyl methylphosphonate and its application to evaluation of nerve agent antidotes. Sarin 35-40 acetylcholinesterase (Cartwright blood group) Homo sapiens 68-88 17096183-0 2006 New safe method for preparation of sarin-exposed human erythrocytes acetylcholinesterase using non-toxic and stable sarin analogue isopropyl p-nitrophenyl methylphosphonate and its application to evaluation of nerve agent antidotes. Sarin 116-121 acetylcholinesterase (Cartwright blood group) Homo sapiens 68-88