PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18544167-0 2008 Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways. 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine 35-47 nuclear factor kappa B subunit 1 Homo sapiens 116-125 18544167-10 2008 The potent and selective apoptotic effects of these drugs suggest that both BMS-345541 and Purvalanol A, which target both NF-kappaB and CDK complex and the G1/S border, might be promising new agents in the treatment of these infected patients. 6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine 91-103 nuclear factor kappa B subunit 1 Homo sapiens 123-132