PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27753495-3 2016 We found the transition concentration is ion-specific, and the capacity of sodium halide salts to inhibit bubble coalescence follows the order of NaF > NaCl > NaBr > NaI. Sodium Chloride 155-159 C-X-C motif chemokine ligand 8 Homo sapiens 146-149 30582047-2 2018 The solubility of NaF in the solutions of NaCl, NaNO3, Na2CO3, Na2SO4 and NaOH at 30 C was determined. Sodium Chloride 42-46 C-X-C motif chemokine ligand 8 Homo sapiens 18-21 23795507-10 2013 However, the degree of ionic absorption within the brush is again ion specific n the order NaCl > NaBr > NaI > NaF at 1 m salt concentration. Sodium Chloride 91-95 C-X-C motif chemokine ligand 8 Homo sapiens 120-123 27308826-10 2016 Interestingly, there was a mean increase in all inflammatory cytokines (IL-1beta, IL-6, and IL-8) during the saline treatment from day 1 to week 3, whereas during the Tyloxapol treatment, all cytokines decreased. Sodium Chloride 109-115 C-X-C motif chemokine ligand 8 Homo sapiens 92-96 26611525-9 2016 Aspect of patients, 0.45% NaCl group and 0.9% NaCl+ambroxol group were significantly different in the levels of SP-A, IL-6, IL-8 and TNF-alpha (P<0.01). Sodium Chloride 26-30 C-X-C motif chemokine ligand 8 Homo sapiens 124-128 26611525-9 2016 Aspect of patients, 0.45% NaCl group and 0.9% NaCl+ambroxol group were significantly different in the levels of SP-A, IL-6, IL-8 and TNF-alpha (P<0.01). Sodium Chloride 46-50 C-X-C motif chemokine ligand 8 Homo sapiens 124-128 23795509-5 2013 Its maximum, however, is shifted towards higher DOTAP concentrations in the row: NaF < NaCl < NaBr. Sodium Chloride 90-94 C-X-C motif chemokine ligand 8 Homo sapiens 81-84 18837496-10 2008 The hydration number N h and the dielectric relaxation property of the hydration layer for each salt solution was successfully determined as ( f c1, delta 1, N h)= (18.7, 44.9, 27.9) for NaCl and ( f c1, delta 1, f c2, delta 2, N h) = (26.0, 6.70, 5.64, 19.2) for NaF. Sodium Chloride 187-191 C-X-C motif chemokine ligand 8 Homo sapiens 264-267 21330456-0 2011 Nebulized hypertonic saline decreases IL-8 in sputum of patients with cystic fibrosis. Sodium Chloride 21-27 C-X-C motif chemokine ligand 8 Homo sapiens 38-42 21330456-3 2011 Evidence that increased hypertonicity of airway secretions induced by hypertonic saline treatment alters levels of IL-8 is lacking. Sodium Chloride 81-87 C-X-C motif chemokine ligand 8 Homo sapiens 115-119 21330456-4 2011 OBJECTIVES: To investigate the antiinflammatory effect of hypertonic saline (HTS) treatment within the CF lung by focusing on IL-8. Sodium Chloride 58-75 C-X-C motif chemokine ligand 8 Homo sapiens 126-130 21330456-11 2011 Nebulized hypertonic saline treatment disrupts the interaction between glycosaminoglycans and IL-8, rendering IL-8 susceptible to proteolytic degradation with subsequent decrease in neutrophil chemotaxis, thereby facilitating resolution of inflammation. Sodium Chloride 21-27 C-X-C motif chemokine ligand 8 Homo sapiens 94-98 21330456-11 2011 Nebulized hypertonic saline treatment disrupts the interaction between glycosaminoglycans and IL-8, rendering IL-8 susceptible to proteolytic degradation with subsequent decrease in neutrophil chemotaxis, thereby facilitating resolution of inflammation. Sodium Chloride 21-27 C-X-C motif chemokine ligand 8 Homo sapiens 110-114 21241520-6 2011 RESULTS: There was a positive correlation between RDR to mannitol and eosinophil numbers (r = 0.47, p = 0.03) and level of IL-8 (r = 0.46, p = 0.04) in hypertonic saline-induced sputum. Sodium Chloride 163-169 C-X-C motif chemokine ligand 8 Homo sapiens 123-127 16388589-7 2006 A comparison of the effects of NaCl/KCl with NaF showed that homeodomain binding results in a release not only of cations from the DNA phosphates but also of chloride ions specifically associated with the proteins. Sodium Chloride 31-35 C-X-C motif chemokine ligand 8 Homo sapiens 45-48 17172977-7 2007 The addition of NaCl lowered the production of IL-8, TNF-alpha, and IL-1 receptor antagonist by neutrophils, and IL-8 and IL-1beta by mononuclear cells stimulated with LPS. Sodium Chloride 16-20 C-X-C motif chemokine ligand 8 Homo sapiens 47-51 17172977-7 2007 The addition of NaCl lowered the production of IL-8, TNF-alpha, and IL-1 receptor antagonist by neutrophils, and IL-8 and IL-1beta by mononuclear cells stimulated with LPS. Sodium Chloride 16-20 C-X-C motif chemokine ligand 8 Homo sapiens 113-117 16647268-0 2006 Increased NaCl-induced interleukin-8 production by human bronchial epithelial cells is enhanced by the DeltaF508/W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene. Sodium Chloride 10-14 C-X-C motif chemokine ligand 8 Homo sapiens 23-36 16647268-6 2006 Human bronchial epithelial cells with the DeltaF508/W1282X CFTR mutation produce an exaggerated amount of basal and NaCl-induced IL-8. Sodium Chloride 116-120 C-X-C motif chemokine ligand 8 Homo sapiens 129-133 18767879-5 2008 Phase composition analysis results illustrate that for the ATPS-C formed by 0.10 mol.kg (-1) 12-3-12/AS mixed system, the concentration of Br (-) counterions in the dilute phase of ATPS-C increases with addition of NaF, NaCl, NaHCO 3, or NaNO 3. Sodium Chloride 220-224 C-X-C motif chemokine ligand 8 Homo sapiens 215-218 11378323-7 2001 We found that 0.5 M NaCl treatment increased mRNA levels of proinflammatory cytokines such as IL-1alpha, IL-6 and IL-8 as well as ICAM-1 in NHEK and IL-1alpha, IL-1beta and IL-6 mRNA levels in NHDF. Sodium Chloride 20-24 C-X-C motif chemokine ligand 8 Homo sapiens 114-118 15805230-7 2005 In DMOG-pretreated (20 mg/kg) animals, plasma IL-8 levels at 3 h after onset of reperfusion were 405 +/- 40 pg/ml vs. 790 +/- 40 pg/ml in saline-treated ischemia-reperfusion animals (P < 0.001). Sodium Chloride 138-144 C-X-C motif chemokine ligand 8 Homo sapiens 46-50 20021137-12 2004 Replacement of NaCl with LiCl decreased the L-cysteine uptake by about 5-fold and in the presence of NaF decrease in L-cysteine uptake was about 2 fold. Sodium Chloride 15-19 C-X-C motif chemokine ligand 8 Homo sapiens 101-104 12384994-6 2002 In vitro, IL-8 treated fibroblasts demonstrated an increase in GJIC by scrape loading compared to saline treated controls. Sodium Chloride 98-104 C-X-C motif chemokine ligand 8 Homo sapiens 10-14 12384994-7 2002 In vivo, IL-8 treated PVA sponges demonstrated a decrease in cell density and an increase in vascularization compared to saline controls by H&E staining. Sodium Chloride 121-127 C-X-C motif chemokine ligand 8 Homo sapiens 9-13 15863635-9 2005 Epithelial expression of interleukin-8 showed a tendency towards a significant increase after LPS compared to saline. Sodium Chloride 110-116 C-X-C motif chemokine ligand 8 Homo sapiens 25-38 12951051-0 2003 Reduction of chemokine IL-8 and RANTES expression in human bronchial epithelial cells by a sea-water derived saline through inhibited nuclear factor-kappaB activation. Sodium Chloride 109-115 C-X-C motif chemokine ligand 8 Homo sapiens 23-27 12951051-3 2003 Exposure of BECs to ISW saline caused a significant decrease in IL-8 and RANTES gene expression and protein production as compared to that observed with 0.9% NaCl saline. Sodium Chloride 24-30 C-X-C motif chemokine ligand 8 Homo sapiens 64-68 12507912-2 2003 The present study was undertaken to evaluate the effects of anti-inflammatory cytokine interleukin-10 (IL-10) on NaCl-induced chemokine IL-8 and regulated on activation normal T cell expressed and secreted (RANTES) expression through the NF-kappaB signaling in primary deltaF508 CF and non-CF (control) human bronchial epithelial cells. Sodium Chloride 113-117 C-X-C motif chemokine ligand 8 Homo sapiens 136-140 12507912-4 2003 Compared to non-CF cells, CF bronchial epithelial cells were characterized by a higher susceptibility to produce elevated IL-8 and RANTES production in an hypertonic NaCl milieu in response to IL-1beta activation. Sodium Chloride 166-170 C-X-C motif chemokine ligand 8 Homo sapiens 122-126 11189316-4 1997 In biological activity test of IL-8 inhibitor, using pooled GCF taken from 8 AP patients (23 teeth), the results showed that the GCF (without recombinant human IL-8, rhIL-8) caused more white blood cell (WBC) migration than blank control group (physiological saline) did. Sodium Chloride 259-265 C-X-C motif chemokine ligand 8 Homo sapiens 31-35 10706733-0 2000 High susceptibility for cystic fibrosis human airway gland cells to produce IL-8 through the I kappa B kinase alpha pathway in response to extracellular NaCl content. Sodium Chloride 153-157 C-X-C motif chemokine ligand 8 Homo sapiens 76-80 11027515-3 2000 Hyperosmolarity (NaCl) caused a time- and concentration-dependent increase in IL-8 expression and secretion in bronchial epithelial cells. Sodium Chloride 17-21 C-X-C motif chemokine ligand 8 Homo sapiens 78-82 10706733-4 2000 Exposure of non-CF gland cells to hypotonic (85 mM) NaCl solution, compared with isotonic (115 mM) NaCl and hypertonic (170 mM) NaCl solutions, resulted in a significant decrease in IL-8 production that was paralleled by a strong inhibition of activated NF-kappa B associated with an increased cytosolic expression of I kappa B alpha and a decrease in the I kappa B kinase alpha protein level. Sodium Chloride 52-56 C-X-C motif chemokine ligand 8 Homo sapiens 182-186 10706733-7 2000 This is the first demonstration that primary human CF bronchial gland cells exhibit abnormally high IL-8 production through constitutively activated NF-kappa B and high I kappa B kinase alpha level, whatever the hypo-, iso-, and hypertonic NaCl milieu. Sodium Chloride 240-244 C-X-C motif chemokine ligand 8 Homo sapiens 100-104 9698935-8 1997 Furthermore, the chemotactic activity of SAL-stimulated mast cells was inhibited by antisera against IL-5 and IL-8 (interleukins). Sodium Chloride 41-44 C-X-C motif chemokine ligand 8 Homo sapiens 110-114 9087177-4 1997 In contrast, exposure of PBMC to hyperosmotic conditions (330-410 mOsM) by the addition of NaCl to tissue culture medium induced gene expression for IL-1 alpha, IL-1 beta, and IL-8. Sodium Chloride 91-95 C-X-C motif chemokine ligand 8 Homo sapiens 176-180 9146930-10 1997 For healthy subjects and the four patients exposed to saline, the level of IL-8 did not increase after challenge in comparison with that at baseline. Sodium Chloride 54-60 C-X-C motif chemokine ligand 8 Homo sapiens 75-79 9698935-9 1997 SAL-stimulated MO were only inhibited by anti-IL-8 antibodies as well SEP-stimulated mast cells. Sodium Chloride 0-3 C-X-C motif chemokine ligand 8 Homo sapiens 46-50 9698935-10 1997 These results suggest that the EO migration induced by SAL may be dependent on resident mast cells and MO and mediated by LTB4, IL-5 and IL-8. Sodium Chloride 55-58 C-X-C motif chemokine ligand 8 Homo sapiens 137-141 29016269-6 1993 In the presence of NaCl, Na2SO4, MgClg, CaCl2, NaF and urea, the adsorption was slightly affected. Sodium Chloride 19-23 C-X-C motif chemokine ligand 8 Homo sapiens 47-50 41586-5 1979 The solubilized monoacylglycerol hydrolase from platelets was optimally active at pH between 7 and 8 and at ionic strength corresponding to [NaCl] between 0.1 and 0.3 M. The optimal assay temperature was 37 degrees C. The enzyme activity was sensitive to HgCl2 but not to NaF. Sodium Chloride 141-145 C-X-C motif chemokine ligand 8 Homo sapiens 272-275 8756824-2 1996 We have investigated the profile of cellular recruitment into asthmatic airways after allergen and saline exposure and its relationship to interleukin-8 (IL-8) release. Sodium Chloride 99-105 C-X-C motif chemokine ligand 8 Homo sapiens 154-158 8756824-10 1996 There was a significant correlation between neutrophil numbers and IL-8 concentrations 4 h after saline exposure. Sodium Chloride 97-103 C-X-C motif chemokine ligand 8 Homo sapiens 67-71 8618875-5 1995 Hyperosmolar NaCl also induced IL-8 and increased steady-state levels of IL-8 mRNA similar to those induced by IL-1 alpha. Sodium Chloride 13-17 C-X-C motif chemokine ligand 8 Homo sapiens 31-35 8618875-5 1995 Hyperosmolar NaCl also induced IL-8 and increased steady-state levels of IL-8 mRNA similar to those induced by IL-1 alpha. Sodium Chloride 13-17 C-X-C motif chemokine ligand 8 Homo sapiens 73-77 8618875-6 1995 IL-8 gene expression was elevated for 96 hr in peripheral blood mononuclear cells incubated with hyperosmolar NaCl. Sodium Chloride 110-114 C-X-C motif chemokine ligand 8 Homo sapiens 0-4 8618875-7 1995 In human THP-1 macrophagic cells, osmotic stimulation with KI, NaI, or NaCl also induced IL-8 production. Sodium Chloride 71-75 C-X-C motif chemokine ligand 8 Homo sapiens 89-93 8618875-9 1995 Using specific blockade of this kinase, a dose-response inhibition of hyperosmolar NaCl-induced IL-8 synthesis was observed, similar to that in cells stimulated with IL-1. Sodium Chloride 83-87 C-X-C motif chemokine ligand 8 Homo sapiens 96-100 3114629-8 1987 (2) NaCl is weakly clastogenic at 1000 times the threshold dose for NaF. Sodium Chloride 4-8 C-X-C motif chemokine ligand 8 Homo sapiens 68-71 6325278-4 1984 Within an alkali cation series (e.g. NaCH3CO2, NaF, NaCl, NaBr, NaNO3, NaI or a similar potassium series) the affinity decreased with decreasing B coefficient of viscosity. Sodium Chloride 52-56 C-X-C motif chemokine ligand 8 Homo sapiens 47-50 1068502-4 1976 The F uptake by enamel surfaces from 0.25 mM NaF in 175 mM NaCl, corresponding to a dish prepared with salt containing 500 parts/106 F, was about 80% greater than from the same NaF concentration in water. Sodium Chloride 59-63 C-X-C motif chemokine ligand 8 Homo sapiens 45-48