PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18372278-11 2008 Enalapril and the combination of enalapril plus spironolactone efficiently reduce PAI-1 levels, but the reductions are more pronounced with the combined regimen. Enalapril 0-9 serpin family E member 1 Homo sapiens 82-87 19707983-6 2009 RESULTS: In the enalapril group PAI-1 levels were significantly reduced after treatment (11.9 +/- 2.3 U/ml vs. 17.1 +/- 3.0 U/l; P < 0.05). Enalapril 16-25 serpin family E member 1 Homo sapiens 32-37 18372278-11 2008 Enalapril and the combination of enalapril plus spironolactone efficiently reduce PAI-1 levels, but the reductions are more pronounced with the combined regimen. Enalapril 33-42 serpin family E member 1 Homo sapiens 82-87 11859853-4 2002 PAI-1 decreased significantly in both genders in the enalapril-treated group after two weeks, with a maximum decrease at six months (mean reduction: 31% equal to 9.8 microg x L(-1), CI: 5.2 to 14.5 microg x L(-1), p = 0.0001) and remained significantly lower at 12 months. Enalapril 53-62 serpin family E member 1 Homo sapiens 0-5 14747423-7 2004 PAI-1 antigen trended toward being lower with quinapril versus enalapril on day 1 (24.44 +/- 14.96 vs. 36.94 +/- 19.49, respectively, p = 0.059) and was significantly lower on day 3 (17.32 +/- 9.57 vs. 27.49 +/- 9.61, respectively, p = 0.009). Enalapril 63-72 serpin family E member 1 Homo sapiens 0-5 11859853-6 2002 The tPA/PAI-1-complex decreased and was significantly lower (mean reduction 0.96 microg x L(-1), CI: 0.36 to 1.56 microg x L(-1), p = 0.003) in the enalapril group after two weeks and six months (p = 0.037). Enalapril 148-157 serpin family E member 1 Homo sapiens 8-13 11859853-8 2002 CONCLUSIONS: Enalapril treatment up to one year depressed mass concentrations of PAI-1 and transiently tPA and tPA/PAI-1 complex indicating an improvement of the fibrinolytic balance in both genders with uncomplicated myocardial infarction. Enalapril 13-22 serpin family E member 1 Homo sapiens 81-86 11859853-8 2002 CONCLUSIONS: Enalapril treatment up to one year depressed mass concentrations of PAI-1 and transiently tPA and tPA/PAI-1 complex indicating an improvement of the fibrinolytic balance in both genders with uncomplicated myocardial infarction. Enalapril 13-22 serpin family E member 1 Homo sapiens 115-120 1873917-4 1991 After captopril (acute) and enalapril (chronic), PAI and PRA increased, PAII decreased, but neither UV-AI nor UV-AII changed. Enalapril 28-37 serpin family E member 1 Homo sapiens 49-52 10347337-10 1999 In the enalapril group, there was no significant change in tPA although PAI-1 activity significantly decreased after drug treatment. Enalapril 7-16 serpin family E member 1 Homo sapiens 72-77 7661384-3 1995 In the current study the authors have investigated the effect of two ACE inhibitors, captopril and enalapril, on tissue plasminogen activator (tPA) and PAI in 33 congestive heart failure (CHF) patients. Enalapril 99-108 serpin family E member 1 Homo sapiens 152-155 32125188-3 2020 In this study, we hypothesized that the beneficial effect of the angiotensin-converting enzyme inhibitor (ACEi) enalapril on PAI-1 levels is mediated by effects on leptin levels. Enalapril 112-121 serpin family E member 1 Homo sapiens 125-130