PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11756416-0	2002	Lithium induces NF-kappa B activation and interleukin-8 production in human intestinal epithelial cells.	Lithium	0-7	C-X-C motif chemokine ligand 8	Homo sapiens	42-55	
19407340-4	2009	Herein, we show that lithium induces a rapid and pronounced up-regulation of the matrix metalloproteinase (MMP)-1, an inflammation and senescent cell marker, at the mRNA and protein levels, whereas the induction of two other senescent cell markers is either weak (interleukin-8) or delayed (plasminogen activator inhibitor-1).	Lithium	21-28	C-X-C motif chemokine ligand 8	Homo sapiens	264-277	
11756416-5	2002	This lithium-induced up-regulation of NF-kappa B and MAP kinase activation was associated with an enhancement of interleukin-8 mRNA accumulation as well as an increase in interleukin-8 protein release.	Lithium	5-12	C-X-C motif chemokine ligand 8	Homo sapiens	113-126	
11756416-5	2002	This lithium-induced up-regulation of NF-kappa B and MAP kinase activation was associated with an enhancement of interleukin-8 mRNA accumulation as well as an increase in interleukin-8 protein release.	Lithium	5-12	C-X-C motif chemokine ligand 8	Homo sapiens	171-184	
26201230-1	2015	PURPOSE: To analyze whether immersion in sodium fluoride (NaF) solutions and/or common acidic beverages (test solutions) would affect the surface roughness or topography of lithium disilicate ceramic.	Lithium	173-180	C-X-C motif chemokine ligand 8	Homo sapiens	58-61	
10855853-1	2000	AIMS AND BACKGROUND: Since interleukin-8 (IL-8) has a suppressive effect on hematopoiesis, lithium induces leukocytosis and granulocytosis and mononuclear cells are defective in patients affected by neoplastic disease, we analyzed IL-8 production by monocytes obtained from patients with nonmetastatic breast cancer (BCaM0) and metastatic breast cancer (BCaM1) and the effect of lithium chloride (LiCl) on these cells.	Lithium	91-98	C-X-C motif chemokine ligand 8	Homo sapiens	231-235	
10855853-3	2000	Lithium influences the hematopoietic system, which is known to be regulated by numerous cytokines including IL-8.	Lithium	0-7	C-X-C motif chemokine ligand 8	Homo sapiens	108-112	
10855853-12	2000	Lithium was able to downregulate IL-8 production by monocytes from different subgroups.	Lithium	0-7	C-X-C motif chemokine ligand 8	Homo sapiens	33-37	
10367558-5	1999	Lithium (10(-3) M) significantly increased the unstimulated production of IL-8 and IL-10.	Lithium	0-7	C-X-C motif chemokine ligand 8	Homo sapiens	74-78	
10367558-6	1999	CONCLUSIONS: The results suggest that lithium has significant immunoregulatory effects by increasing the production of both proinflammatory cytokines (IFNgamma, TNFalpha and IL-8) and negative immunoregulatory cytokines or proteins (IL-10 and the IL-1RA).	Lithium	38-45	C-X-C motif chemokine ligand 8	Homo sapiens	174-178	
27639185-5	2017	VPA and lithium both induce significant down-regulation of group I CD1 expression and secretion of IL-6 during differentiation of human monocyte-derived immature DC, while they differ in the induction of CD83 and CD86 expression, secretion of IL-8, IL-10, and TNF-alpha.	Lithium	8-15	C-X-C motif chemokine ligand 8	Homo sapiens	243-247	
25451615-0	2015	Increased cerebrospinal fluid interleukin-8 in bipolar disorder patients associated with lithium and antipsychotic treatment.	Lithium	89-96	C-X-C motif chemokine ligand 8	Homo sapiens	30-43	
25451615-8	2015	IL-8 concentrations were positively associated to lithium- and antipsychotic treatment.	Lithium	50-57	C-X-C motif chemokine ligand 8	Homo sapiens	0-4