PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12404604-6	2001	In vitro, it has been shown that various types of antidepressive drugs, including TCAs (imipramine; clomipramine); SSRIs (citalopram, fluoxetine, sertraline); lithium; SNRIs (venlafaxine); HCAs (trazodone); RIMAs (moclobemide) and L-5-HTP significantly suppress the ratio of IFNgamma/IL-10 production by peripheral blood immunocytes.	Lithium	159-166	interferon gamma	Homo sapiens	275-283	
15488263-5	2004	RESULTS: BAD patients under chronic lithium treatment had significantly lower numbers of IL-2, IL-6, IL-10 and IFN-gamma secreting cells compared to healthy volunteers.	Lithium	36-43	interferon gamma	Homo sapiens	111-120	
15488263-8	2004	CONCLUSIONS: The significantly lower number of PBLs producing cytokines (IL-2, IL-6, IL-10 and IFN-gamma) in euthymic BAD patients under chronic lithium treatment result from the long-term (over 3 months) lithium administration.	Lithium	145-152	interferon gamma	Homo sapiens	95-104	
14506314-7	2003	Lithium differed significantly from imipramine and mianserin, as it enhanced IL-2, IFN-gamma, IL-10 and TGF-beta production and inhibited only IL-4.	Lithium	0-7	interferon gamma	Homo sapiens	83-92	
11513821-4	2001	RESULTS: We found that lithium caused an increase in interleukin-4 and interleukin-10 levels, traditionally classified as T-helper lymphocyte type-2 cytokines, and a decrease in interleukin-2 and interferon-gamma levels, traditionally classified as T-helper lymphocyte type-1 (TH-1) cytokines.	Lithium	23-30	interferon gamma	Homo sapiens	196-212	
10367558-6	1999	CONCLUSIONS: The results suggest that lithium has significant immunoregulatory effects by increasing the production of both proinflammatory cytokines (IFNgamma, TNFalpha and IL-8) and negative immunoregulatory cytokines or proteins (IL-10 and the IL-1RA).	Lithium	38-45	interferon gamma	Homo sapiens	151-159	
34088327-8	2021	RESULTS: Lithium was shown to stimulate interferon-gamma (IFN-gamma) production as early as 3 h pi.	Lithium	9-16	interferon gamma	Homo sapiens	40-56	
34088327-8	2021	RESULTS: Lithium was shown to stimulate interferon-gamma (IFN-gamma) production as early as 3 h pi.	Lithium	9-16	interferon gamma	Homo sapiens	58-67	
8967788-5	1996	Il-6 levels were slightly elevated in the supernatants obtained from psoriatic and control keratinocyte cultures after lithium treatment, but IFN gamma and Il-2 levels were elevated only in the lithium-treated cocultures with psoriatic keratinocytes.	Lithium	194-201	interferon gamma	Homo sapiens	142-151	
8967788-8	1996	We therefore demonstrated that lithium influences the cell communication of psoriatic keratinocytes with HUT 78 lymphocytes by triggering the secretion of TGF alpha, Il-2 and, massively, IFN gamma.	Lithium	31-38	interferon gamma	Homo sapiens	187-196	
34862988-5	2022	Lithium counteracted these effects, increasing inhibitory GSK3betaS9 phosphorylation and reducing STAT1S727 and STAT3Y705 phosphorylation levels in IFN-gamma treated cells.	Lithium	0-7	interferon gamma	Homo sapiens	148-157