PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11246122-3 2001 Mucous differentiation and expression of MUC2, MUC5AC, MUC5B and MUC7, but not MUCi, MUC4, and MUC8 mucin genes, were shown to be retinoic acid- (RA) or retinol-dependent. Tretinoin 130-143 mucin 2, oligomeric mucus/gel-forming Homo sapiens 41-45 12042033-6 2002 We previously reported that induction of MUC2, MUC5AC, and MUC5B gene expressions by retinoic acid is mediated by the retinoic acid receptor (RARalpha), and inhibited by the specific RARalpha antagonist Ro 41-5253. Tretinoin 85-98 mucin 2, oligomeric mucus/gel-forming Homo sapiens 41-45 18368492-5 2008 Retinoic acid induces expression of a marker of intestinal differentiation, MUC2, in these cells. Tretinoin 0-13 mucin 2, oligomeric mucus/gel-forming Homo sapiens 76-80 18368492-7 2008 The ability of retinoic acid to induce MUC2 expression may be relevant to the pathogenesis of Barrett"s esophagus. Tretinoin 15-28 mucin 2, oligomeric mucus/gel-forming Homo sapiens 39-43 17646388-3 2007 In the present study, we further demonstrated that this nonclassical signaling of RA on the activation of CREB plays a critical role in regulating the expression of airway epithelial cell differentiation markers, the MUC2, MUC5AC, and MUC5B genes. Tretinoin 82-84 mucin 2, oligomeric mucus/gel-forming Homo sapiens 217-221 11246122-3 2001 Mucous differentiation and expression of MUC2, MUC5AC, MUC5B and MUC7, but not MUCi, MUC4, and MUC8 mucin genes, were shown to be retinoic acid- (RA) or retinol-dependent. Tretinoin 146-148 mucin 2, oligomeric mucus/gel-forming Homo sapiens 41-45 10024510-1 1999 To investigate which retinoid receptors are critical in the regulation by all-trans-retinoic acid (RA) of the mucin genes MUC2, MUC5AC and MUC5B in cultured normal human tracheobronchial epithelial (NHTBE) cells, we used pan-RAR-, pan-RXR- and RAR- isotype (alpha, beta and gamma)-selective agonists and RARalpha- and RARgamma-selective antagonists (RAR is RA receptor and RXR is retinoid X receptor). Tretinoin 84-97 mucin 2, oligomeric mucus/gel-forming Homo sapiens 122-126 11200589-7 2000 Omission of retinoic acid (RA) caused decrease in the secretion of mucin and lysozyme, and in the cellular expression of MUC 2, MUC 5AC and MUC 5B mRNA. Tretinoin 12-25 mucin 2, oligomeric mucus/gel-forming Homo sapiens 121-126 11200589-7 2000 Omission of retinoic acid (RA) caused decrease in the secretion of mucin and lysozyme, and in the cellular expression of MUC 2, MUC 5AC and MUC 5B mRNA. Tretinoin 27-29 mucin 2, oligomeric mucus/gel-forming Homo sapiens 121-126 10953040-2 2000 In HTBE cells, retinoic acid (RA) inhibits squamous differentiation and induces mucous cell differentiation as indicated by the suppression of transglutaminase I and increased expression of the mucin gene MUC2. Tretinoin 15-28 mucin 2, oligomeric mucus/gel-forming Homo sapiens 205-209 10953040-2 2000 In HTBE cells, retinoic acid (RA) inhibits squamous differentiation and induces mucous cell differentiation as indicated by the suppression of transglutaminase I and increased expression of the mucin gene MUC2. Tretinoin 30-32 mucin 2, oligomeric mucus/gel-forming Homo sapiens 205-209 10953040-4 2000 RA is required but not sufficient to induce RARbeta, CYP26, and MUC2 mRNA because induction is only observed in confluent but not in logarithmic cultures, suggesting that additional factors are critical in their regulation. Tretinoin 0-2 mucin 2, oligomeric mucus/gel-forming Homo sapiens 64-68 10024510-1 1999 To investigate which retinoid receptors are critical in the regulation by all-trans-retinoic acid (RA) of the mucin genes MUC2, MUC5AC and MUC5B in cultured normal human tracheobronchial epithelial (NHTBE) cells, we used pan-RAR-, pan-RXR- and RAR- isotype (alpha, beta and gamma)-selective agonists and RARalpha- and RARgamma-selective antagonists (RAR is RA receptor and RXR is retinoid X receptor). Tretinoin 99-101 mucin 2, oligomeric mucus/gel-forming Homo sapiens 122-126 9191474-5 1997 Removal of RA from the media caused a drastic decrease in mucin secretion and a decrease in expression of the mucin genes MUC2 and MUC5AC.LZ and SLPI secretions were increased in these cultures. Tretinoin 11-13 mucin 2, oligomeric mucus/gel-forming Homo sapiens 122-126