PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8262951-0	1993	Retinol bound to cellular retinol-binding protein is a substrate for cytosolic retinoic acid synthesis.	Tretinoin	79-92	retinol binding protein 1	Bos taurus	17-49	
8262951-1	1993	Retinol bound to cellular retinol-binding protein (CRBP) was found to be oxidized to retinoic acid by a soluble activity from calf liver.	Tretinoin	85-98	retinol binding protein 1	Bos taurus	17-49	
8262951-1	1993	Retinol bound to cellular retinol-binding protein (CRBP) was found to be oxidized to retinoic acid by a soluble activity from calf liver.	Tretinoin	85-98	retinol binding protein 1	Bos taurus	51-55	
8262951-2	1993	Cytosolic retinoic acid synthesis from retinol-CRBP was strictly dependent on the exogenous supply of either NAD or NADP.	Tretinoin	10-23	retinol binding protein 1	Bos taurus	47-51	
8262951-5	1993	Since the dissociation constant of the bovine retinol-CRBP complex is less than 10(-8) M, whereas the Km for retinol-CRBP is of the same order as the Km for free retinol, synthesis of retinoic acid from retinol-CRBP does not rely on prior dissociation of retinol.	Tretinoin	184-197	retinol binding protein 1	Bos taurus	54-58	
8262951-5	1993	Since the dissociation constant of the bovine retinol-CRBP complex is less than 10(-8) M, whereas the Km for retinol-CRBP is of the same order as the Km for free retinol, synthesis of retinoic acid from retinol-CRBP does not rely on prior dissociation of retinol.	Tretinoin	184-197	retinol binding protein 1	Bos taurus	117-121	
8262951-5	1993	Since the dissociation constant of the bovine retinol-CRBP complex is less than 10(-8) M, whereas the Km for retinol-CRBP is of the same order as the Km for free retinol, synthesis of retinoic acid from retinol-CRBP does not rely on prior dissociation of retinol.	Tretinoin	184-197	retinol binding protein 1	Bos taurus	117-121	
8262951-6	1993	ApoCRBP proved to be a specific inhibitor of retinoic acid synthesis from CRBP-bound retinol.	Tretinoin	45-58	retinol binding protein 1	Bos taurus	3-7	
8262951-9	1993	These results indicate that the protein moiety of holoCRBP is specifically recognized by the cytosolic enzyme system that catalyzes retinoic acid synthesis from CRBP-bound retinol.	Tretinoin	132-145	retinol binding protein 1	Bos taurus	54-58