PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18926686-6	2009	Retinoic acid also repressed LPS-induced transcription of NF-kappaB target genes such as IL-6, MCP-1 and COX-2.	Tretinoin	0-13	C-C motif chemokine ligand 2	Homo sapiens	95-100	
12115542-7	2002	Owing to a decrease in the secretion of MCP-1 and transforming growth factor-beta 1 (TGF-beta 1), tumor cells treated with RA were unable to induce peripheral blood monocyte (PBM) chemotaxis.	Tretinoin	123-125	C-C motif chemokine ligand 2	Homo sapiens	40-45	
18216048-2	2008	The current study investigated the role of monocyte chemotactic protein (MCP)-1 in the chemotactic transmigration of ATRA-treated NB4 (ATRA-NB4) APL cells toward A549 alveolar epithelial cells.	Tretinoin	117-121	C-C motif chemokine ligand 2	Homo sapiens	43-79	
18216048-6	2008	The secretion of MCP-1 was enhanced by ATRA treatment in both A549 and NB4 cells.	Tretinoin	39-43	C-C motif chemokine ligand 2	Homo sapiens	17-22	
18216048-10	2008	Monocyte chemotactic protein-1 secreted from alveolar epithelial cells plays an important role in the cell-cell interaction involved in the chemotactic transmigration of all-trans retinoic acid-treated acute promyelocytic leukaemia cells toward alveolar epithelial cells.	Tretinoin	180-193	C-C motif chemokine ligand 2	Homo sapiens	0-30	
15927671-3	2005	The RNase protection assay using a multi-probe template set for human chemokines revealed that ATRA induced gene expressions of a number of CC chemokines, such as monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in NB4 cells.	Tretinoin	95-99	C-C motif chemokine ligand 2	Homo sapiens	163-197	
15927671-3	2005	The RNase protection assay using a multi-probe template set for human chemokines revealed that ATRA induced gene expressions of a number of CC chemokines, such as monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein (MIP)-1alpha and MIP-1beta in NB4 cells.	Tretinoin	95-99	C-C motif chemokine ligand 2	Homo sapiens	199-204	
15927671-5	2005	APL cells prepared from two APL patients showed gene expression of chemokines, such as IL-8, MCP-1, MIP-1alpha, and MIP-1beta when stimulated with ATRA in vitro.	Tretinoin	147-151	C-C motif chemokine ligand 2	Homo sapiens	93-98	
1365641-12	1992	In contrast, retinoic acid strongly increased phorbol myristate acetate-induced MCP-1 expression and potentiated the effects of IL-1 and LPS.	Tretinoin	13-26	C-C motif chemokine ligand 2	Homo sapiens	80-85	
10479651-3	1999	In the current study, we show 9-cis retinoic acid (RA), a ligand for the nuclear hormone receptor retinoid X receptor (RXR) and retinoic acid receptor (RAR), markedly induces the expression of MCP-1.	Tretinoin	51-53	C-C motif chemokine ligand 2	Homo sapiens	193-198	
10479651-4	1999	In human THP-1 monocytic leukemia cells cultured with RA (0.05 to 500 nmol/L), MCP-1 expression was induced rapidly, significantly, and dose-dependently by as much as 165-fold.	Tretinoin	54-56	C-C motif chemokine ligand 2	Homo sapiens	79-84	
10479651-11	1999	These studies identify RA as a nuclear signal for MCP-1 induction in undifferentiated human monocytic cells.	Tretinoin	23-25	C-C motif chemokine ligand 2	Homo sapiens	50-55	
7919389-0	1994	Monocyte chemoattractant protein-1 gene is expressed in activated neutrophils and retinoic acid-induced human myeloid cell lines.	Tretinoin	82-95	C-C motif chemokine ligand 2	Homo sapiens	0-34	
7919389-2	1994	Three of the cDNAs cloned hybridized to RA-inducible transcripts on Northern blots, one of which was shown to encode sequences for monocyte chemoattractant protein-1 (MCP-1), a recently described cytokine that is chemotactic for monocytes but not for neutrophils.	Tretinoin	40-42	C-C motif chemokine ligand 2	Homo sapiens	131-165	
7919389-2	1994	Three of the cDNAs cloned hybridized to RA-inducible transcripts on Northern blots, one of which was shown to encode sequences for monocyte chemoattractant protein-1 (MCP-1), a recently described cytokine that is chemotactic for monocytes but not for neutrophils.	Tretinoin	40-42	C-C motif chemokine ligand 2	Homo sapiens	167-172	
7919389-4	1994	MCP-1 transcript levels also increased after RA treatment of the NB4 acute promyelocytic cell line.	Tretinoin	45-47	C-C motif chemokine ligand 2	Homo sapiens	0-5	
1624809-4	1992	Expression of the MCP-1 gene is inducible by activators of the protein kinase A (cAMP) and C (PMA) signal transduction pathways and is differentially regulated by the steroids dexamethasone and retinoic acid.	Tretinoin	194-207	C-C motif chemokine ligand 2	Homo sapiens	18-23	
32663289-0	2020	Retinoic Acid Potentiates Orbital Tissues for Inflammation Through NF-kappaB and MCP-1.	Tretinoin	0-13	C-C motif chemokine ligand 2	Homo sapiens	81-86	
32431691-5	2020	We extended these findings to human Mphi THP-1 cells and showed that ATRA synergistically increased IL-4-induced CCL2, CCL13, and CCL26 mRNA and protein levels.	Tretinoin	69-73	C-C motif chemokine ligand 2	Homo sapiens	113-117	
32168763-6	2020	The irreversible inhibitor of TG2 NC9 not only decreased reactive oxygen species production 28-fold, but decreased the concentration of MCP-1, IL-1beta and TNF-alpha 8-, 15- and 61-fold, respectively in the combined ATRA + ATO-treated wild-type NB4 cell culture.	Tretinoin	216-220	C-C motif chemokine ligand 2	Homo sapiens	136-141