PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23337719-11 2013 CONCLUSIONS: Simvastatin interacts with the RA system, inducing the expression of the key protein regulating the uptake of retinol (STRA6) and the expression of apoptosis-promoting CRABP2. Tretinoin 44-46 signaling receptor and transporter of retinol STRA6 Homo sapiens 132-137 19860856-6 2010 Retinoid synthetic enzymes and the retinol transport protein Stra6 were located in the cells lining the third ventricle allowing synthesis of RA from retinol present in the CNS to act via RA receptors and retinoid X receptors in the hypothalamus. Tretinoin 142-144 signaling receptor and transporter of retinol STRA6 Homo sapiens 61-66 20501978-9 2010 We propose other candidates such as STRA6, LRAT, CRBP1, CRBP2 and CRABP1 are directly implicated in retinoic acid metabolism. Tretinoin 100-113 signaling receptor and transporter of retinol STRA6 Homo sapiens 36-41 17867372-3 2007 Recently, it was identified as an integral transmembrane protein named STRA6 that is inducible by retinoic acid in certain cancer cells. Tretinoin 98-111 signaling receptor and transporter of retinol STRA6 Homo sapiens 71-76 18652909-9 2009 In addition, we found that both retinoic acid and retinol induced transcripts for the STRA6 gene, which encodes a membrane receptor involved in retinol (vitamin A) uptake, in PrEC cells but not in PC-3 cells. Tretinoin 32-45 signaling receptor and transporter of retinol STRA6 Homo sapiens 86-91 34945773-1 2021 BACKGROUND: Recent reports indicate the potential role of the stimulated by retinoic acid 6 (STRA6) protein in developing insulin resistance. Tretinoin 76-89 signaling receptor and transporter of retinol STRA6 Homo sapiens 93-98 17503335-2 2007 STRA6 encodes an integral cell-membrane protein that favors RA uptake from soluble retinol-binding protein; its transcription is directly regulated by RA levels. Tretinoin 60-62 signaling receptor and transporter of retinol STRA6 Homo sapiens 0-5 11358845-0 2001 Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid. Tretinoin 22-35 signaling receptor and transporter of retinol STRA6 Homo sapiens 52-57 11358845-6 2001 Accordingly, treatment of human colorectal cancer cell lines with retinoic acid resulted in the up-regulation of Stra6 mRNA and accumulation of Stra6 protein at the cell membrane. Tretinoin 66-79 signaling receptor and transporter of retinol STRA6 Homo sapiens 113-118 11358845-6 2001 Accordingly, treatment of human colorectal cancer cell lines with retinoic acid resulted in the up-regulation of Stra6 mRNA and accumulation of Stra6 protein at the cell membrane. Tretinoin 66-79 signaling receptor and transporter of retinol STRA6 Homo sapiens 144-149 9203140-2 1997 A new retinoic acid-inducible gene, Stra6, has been identified in P19 embryonal carcinoma cells using a subtractive hybridization cDNA cloning technique. Tretinoin 6-19 signaling receptor and transporter of retinol STRA6 Homo sapiens 36-41 23449393-1 2013 Stra6 is the retinoic acid (RA)-inducible gene encoding the cellular receptor for holo-retinol binding protein. Tretinoin 13-26 signaling receptor and transporter of retinol STRA6 Homo sapiens 0-5 34836244-6 2021 All-trans retinol also travels through the bloodstream bound to retinol binding protein 4 (RBP4), where it enters cells with the assistance of the transmembrane transporters, stimulated by retinoic acid 6 (STRA6) in peripheral tissues or retinol binding protein 4 receptor 2 (RBPR2) in systemic tissues (e.g., in the retina and the liver, respectively). Tretinoin 189-202 signaling receptor and transporter of retinol STRA6 Homo sapiens 206-211 33273838-2 2020 Recent studies have analyzed the impact of the two adipokines, RBP4 (retinol binding protein 4) and STRA6 (stimulated by retinoic acid 6) in pediatric obese subjects with contradictory results. Tretinoin 121-134 signaling receptor and transporter of retinol STRA6 Homo sapiens 100-105 32488128-10 2021 Similarly, in patients without clozapine treatment, mRNA expression of RA-inducible targets CYP26A and STRA6, as well as at-RA/retinol ratio, were significantly reduced. Tretinoin 71-73 signaling receptor and transporter of retinol STRA6 Homo sapiens 103-108 31283017-9 2019 mRNAs of genes involved in retinoic acid (RA) synthesis (Stra6 and Rdh10) were also increased by EtOH, AcH, and 4-HNE treatment. Tretinoin 27-40 signaling receptor and transporter of retinol STRA6 Homo sapiens 57-62 31283017-9 2019 mRNAs of genes involved in retinoic acid (RA) synthesis (Stra6 and Rdh10) were also increased by EtOH, AcH, and 4-HNE treatment. Tretinoin 42-44 signaling receptor and transporter of retinol STRA6 Homo sapiens 57-62 32597569-1 2020 BACKGROUND: Syndromic microphthalmia-9 (MCOPS9) is a rare autosomal recessive disorder caused by mutations in STRA6, an important regulator of vitamin A and retinoic acid metabolism. Tretinoin 157-170 signaling receptor and transporter of retinol STRA6 Homo sapiens 40-46 32597569-1 2020 BACKGROUND: Syndromic microphthalmia-9 (MCOPS9) is a rare autosomal recessive disorder caused by mutations in STRA6, an important regulator of vitamin A and retinoic acid metabolism. Tretinoin 157-170 signaling receptor and transporter of retinol STRA6 Homo sapiens 110-115 31597015-1 2020 AIMS/INTRODUCTION: Electronegative low-density lipoprotein (L5) is the most atherogenic fraction of low-density lipoprotein and is elevated in people with metabolic syndrome (MetS), whereas the retinol-binding protein 4 receptor (stimulated by retinoic acid 6 [STRA6]) cascade is disrupted in various organs of patients with obesity-related diseases. Tretinoin 244-257 signaling receptor and transporter of retinol STRA6 Homo sapiens 194-228 31953251-0 2020 Correction: An alternative retinoic acid-responsive Stra6 promoter regulated in response to retinol deficiency. Tretinoin 27-40 signaling receptor and transporter of retinol STRA6 Homo sapiens 52-57 32348995-12 2020 At last, we detected stimulated by retinoic acid gene 6 homolog (STRA6), a cell surface receptor formerly known as a gene preventing podocytes from over-proliferative lesion induced by HIV infection and was up-regulated by retinoic acid, expressed at a much higher level in SRNS kidneys. Tretinoin 35-48 signaling receptor and transporter of retinol STRA6 Homo sapiens 65-70 31694721-1 2019 BACKGROUND: Increasing evidence shows that stimulated by retinoic acid 6 (STRA6) participates in regulating multiple cancers. Tretinoin 57-70 signaling receptor and transporter of retinol STRA6 Homo sapiens 74-79 26373900-2 2016 The disorder is caused by mutations in STRA6, an important regulator of vitamin A and retinoic acid metabolism. Tretinoin 86-99 signaling receptor and transporter of retinol STRA6 Homo sapiens 39-44 23449393-1 2013 Stra6 is the retinoic acid (RA)-inducible gene encoding the cellular receptor for holo-retinol binding protein. Tretinoin 28-30 signaling receptor and transporter of retinol STRA6 Homo sapiens 0-5