PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33429696-7	2017	Immunofluorescence studies and RT-PCR revealed that the atRA-loaded biomaterials increased the expression of two epithelial markers of mucociliary differentiation, MUC5AC and beta-tubulin IV, via upregulation of MUC5AC and FOXJ1 genes, both in epithelial monoculture and in a 3D scaffold coculture system with lung fibroblasts.	Tretinoin	56-60	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	164-170	
32266229-8	2020	atRA release from scaffolds led to an increase in mucociliary gene expression at high scaffold loading doses, with augmented MUC5AC and FOXJ1 detected by RT-PCR.	Tretinoin	0-4	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	125-131	
33429696-7	2017	Immunofluorescence studies and RT-PCR revealed that the atRA-loaded biomaterials increased the expression of two epithelial markers of mucociliary differentiation, MUC5AC and beta-tubulin IV, via upregulation of MUC5AC and FOXJ1 genes, both in epithelial monoculture and in a 3D scaffold coculture system with lung fibroblasts.	Tretinoin	56-60	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	212-218	
14977075-9	2004	In addition, the expression of cornifin-alpha mRNA was suppressed, and the expressions of mucin gene 5AC (MUC5AC) and MUC5B mRNA increased progressively with RA treatment.	Tretinoin	158-160	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	90-104	
17646388-3	2007	In the present study, we further demonstrated that this nonclassical signaling of RA on the activation of CREB plays a critical role in regulating the expression of airway epithelial cell differentiation markers, the MUC2, MUC5AC, and MUC5B genes.	Tretinoin	82-84	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	223-229	
14977075-9	2004	In addition, the expression of cornifin-alpha mRNA was suppressed, and the expressions of mucin gene 5AC (MUC5AC) and MUC5B mRNA increased progressively with RA treatment.	Tretinoin	158-160	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	106-112	
12042033-6	2002	We previously reported that induction of MUC2, MUC5AC, and MUC5B gene expressions by retinoic acid is mediated by the retinoic acid receptor (RARalpha), and inhibited by the specific RARalpha antagonist Ro 41-5253.	Tretinoin	85-98	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	47-53	
11246122-3	2001	Mucous differentiation and expression of MUC2, MUC5AC, MUC5B and MUC7, but not MUCi, MUC4, and MUC8 mucin genes, were shown to be retinoic acid- (RA) or retinol-dependent.	Tretinoin	130-143	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	47-53	
11171071-1	2001	We reported previously that the expression of the gene encoding MUC5AC mucin in human airway epithelial cells is controlled by retinoic acid via the retinoic acid receptor (RAR)-alpha and that 3,3",5-tri-iodothyronine (T(3)) inhibits the expression of MUC5AC.	Tretinoin	127-140	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	64-70	
11200589-7	2000	Omission of retinoic acid (RA) caused decrease in the secretion of mucin and lysozyme, and in the cellular expression of MUC 2, MUC 5AC and MUC 5B mRNA.	Tretinoin	12-25	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	128-135	
11200589-7	2000	Omission of retinoic acid (RA) caused decrease in the secretion of mucin and lysozyme, and in the cellular expression of MUC 2, MUC 5AC and MUC 5B mRNA.	Tretinoin	27-29	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	128-135	
10024510-1	1999	To investigate which retinoid receptors are critical in the regulation by all-trans-retinoic acid (RA) of the mucin genes MUC2, MUC5AC and MUC5B in cultured normal human tracheobronchial epithelial (NHTBE) cells, we used pan-RAR-, pan-RXR- and RAR- isotype (alpha, beta and gamma)-selective agonists and RARalpha- and RARgamma-selective antagonists (RAR is RA receptor and RXR is retinoid X receptor).	Tretinoin	99-101	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	128-134	
9191474-5	1997	Removal of RA from the media caused a drastic decrease in mucin secretion and a decrease in expression of the mucin genes MUC2 and MUC5AC.LZ and SLPI secretions were increased in these cultures.	Tretinoin	11-13	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	131-137