PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23710639-5 2013 Under the all-trans-retinoic acid (RA)-induced differentiation condition, spheroids extended neurites and further up-regulated the expression of synaptophysin, NSE, CAMs, and ECM proteins. Tretinoin 10-33 enolase 2 Homo sapiens 160-163 35204719-9 2022 ATRA or UDP-4 treatment significantly upregulated ENO2 and NF1 expression, indicating neuronal differentiation. Tretinoin 0-4 enolase 2 Homo sapiens 50-54 27771902-4 2017 We found that RA treatment for 7 days reduced the cell number and proliferative capacity and induced the expression of adult catecholaminergic/neuronal markers such as tyrosine hydroxylase (TH), beta-III tubulin, and enolase-2. Tretinoin 14-16 enolase 2 Homo sapiens 217-226 27771902-9 2017 Importantly, Trolox co-treatment inhibited the appearance of morphological characteristics such as neurite extension and branching, and decreased the expression of TH, beta-III tubulin, and enolase-2 after a seven-day differentiation with RA, indicating that RS production is a necessary step in this process. Tretinoin 240-242 enolase 2 Homo sapiens 191-200 14743441-5 2004 RA-treated CD133+ cells expressed mRNA transcripts for neuron-specific markers neurofilament proteins (NF-L, -M, -H) and synaptophysin as determined by RT-PCR, structural proteins characteristic of neurons including tubulin beta III and neuron specific enolase (NSE) by Western blot, and neuron-specific markers NeuN and microtubule-associated protein-2 (MAP2) by immunocytochemistry. Tretinoin 0-2 enolase 2 Homo sapiens 237-260 14743441-5 2004 RA-treated CD133+ cells expressed mRNA transcripts for neuron-specific markers neurofilament proteins (NF-L, -M, -H) and synaptophysin as determined by RT-PCR, structural proteins characteristic of neurons including tubulin beta III and neuron specific enolase (NSE) by Western blot, and neuron-specific markers NeuN and microtubule-associated protein-2 (MAP2) by immunocytochemistry. Tretinoin 0-2 enolase 2 Homo sapiens 262-265 29380316-4 2018 In the described method, the SH-SY5Y neuroblastoma cell line is differentiated to neuronal cell which expresses NSE, neuronal marker, and dopamine transporter (DAT) by treatment with all-trans-retinoic acid. Tretinoin 186-206 enolase 2 Homo sapiens 112-115 23710639-5 2013 Under the all-trans-retinoic acid (RA)-induced differentiation condition, spheroids extended neurites and further up-regulated the expression of synaptophysin, NSE, CAMs, and ECM proteins. Tretinoin 35-37 enolase 2 Homo sapiens 160-163 23318218-5 2013 mRNA and protein levels of the neural-markers Nestin, NSE, MAP-2, Tau and Tuj1 were stronger in neural-like cells derived from all-trans retinoic acid-pretreated mesenchymal stem cells than in those not pre-induction. Tretinoin 137-150 enolase 2 Homo sapiens 54-57 23597229-6 2013 Cells treated with 10 muM trans-retinoic acid (RA) for 72 hrs exhibited marked changes in morphology to include neurite extensions; presence of P/Q, N and T-type voltage-gated Ca2+ channels; and expression of neuron specific enolase (NSE), synaptosomal-associated protein 25 (SNAP-25), nicotinic acetylcholine receptor alpha7 (nAChR-alpha7) and other neuronal markers. Tretinoin 26-45 enolase 2 Homo sapiens 209-232 23597229-6 2013 Cells treated with 10 muM trans-retinoic acid (RA) for 72 hrs exhibited marked changes in morphology to include neurite extensions; presence of P/Q, N and T-type voltage-gated Ca2+ channels; and expression of neuron specific enolase (NSE), synaptosomal-associated protein 25 (SNAP-25), nicotinic acetylcholine receptor alpha7 (nAChR-alpha7) and other neuronal markers. Tretinoin 26-45 enolase 2 Homo sapiens 234-237 23597229-6 2013 Cells treated with 10 muM trans-retinoic acid (RA) for 72 hrs exhibited marked changes in morphology to include neurite extensions; presence of P/Q, N and T-type voltage-gated Ca2+ channels; and expression of neuron specific enolase (NSE), synaptosomal-associated protein 25 (SNAP-25), nicotinic acetylcholine receptor alpha7 (nAChR-alpha7) and other neuronal markers. Tretinoin 47-49 enolase 2 Homo sapiens 209-232 23597229-6 2013 Cells treated with 10 muM trans-retinoic acid (RA) for 72 hrs exhibited marked changes in morphology to include neurite extensions; presence of P/Q, N and T-type voltage-gated Ca2+ channels; and expression of neuron specific enolase (NSE), synaptosomal-associated protein 25 (SNAP-25), nicotinic acetylcholine receptor alpha7 (nAChR-alpha7) and other neuronal markers. Tretinoin 47-49 enolase 2 Homo sapiens 234-237 19035249-15 2008 After the ATRA treatment, cells were stained strongly positive, strongly positive and moderately positive by NSE, vimentin and GFAP antibodies, respectively. Tretinoin 10-14 enolase 2 Homo sapiens 109-112