PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19322650-0 2010 SOX9 mediates the retinoic acid-induced HES-1 gene expression in human breast cancer cells. Tretinoin 18-31 SRY-box transcription factor 9 Homo sapiens 0-4 19322650-2 2010 Here we show that retinoic acid induces HES-1 expression via upregulation of transcription factor SOX9. Tretinoin 18-31 SRY-box transcription factor 9 Homo sapiens 98-102 19322650-3 2010 By expressing a dominant negative form of SOX9, disrupting endogenous SOX9 activity, the retinoic acid-induced HES-1 mRNA expression was inhibited. Tretinoin 89-102 SRY-box transcription factor 9 Homo sapiens 42-46 19322650-3 2010 By expressing a dominant negative form of SOX9, disrupting endogenous SOX9 activity, the retinoic acid-induced HES-1 mRNA expression was inhibited. Tretinoin 89-102 SRY-box transcription factor 9 Homo sapiens 70-74 19322650-5 2010 By performing chromatin immunoprecipitation, we showed that SOX9 binding to the HES-1 enhancer was induced by retinoic acid in vivo. Tretinoin 110-123 SRY-box transcription factor 9 Homo sapiens 60-64 19322650-7 2010 The enhancer responded to retinoic acid; furthermore, the expression of a dominant negative SOX9 abolished this response. Tretinoin 26-39 SRY-box transcription factor 9 Homo sapiens 92-96 18628953-8 2008 RA rapidly induced the expression of Sox-9 and ER81, which in turn form a complex on the VE-cadherin promoter and are required to mediate the transcriptional regulation of VE-cadherin by RA. Tretinoin 0-2 SRY-box transcription factor 9 Homo sapiens 37-42 19273910-0 2009 Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid. Tretinoin 104-117 SRY-box transcription factor 9 Homo sapiens 16-20 28735443-8 2017 In situ hybridization analysis showed that RA is able to alter cyp26a1, sox9, tgfbeta2, and id2 spatial distribution; to increase rarbeta, meis2, and hoxb5 expression levels; and has a very modest effect on sox2, fgf10, fgfr2, and shh expression levels. Tretinoin 43-45 SRY-box transcription factor 9 Homo sapiens 72-76 26401661-4 2015 These 2 ovarian factors, together with retinoic acid (RA) action, promote feminization partially through the repression of the masculinizing activities of SOX9, FGF9 and DMRT1. Tretinoin 39-52 SRY-box transcription factor 9 Homo sapiens 155-159