PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34031932-2 2021 Retinoic acid-inducible gene (RIG)-I-like receptors (RLR), including melanoma differentiation-associated protein 5 (MDA5) and RIG-I, recognize the double-strand (ds) virus RNA and induce the production of Type I interferon (Type I IFN) as well as pro-inflammatory cytokines like Interleukin (IL)-6. Tretinoin 0-13 DExH-box helicase 58 Homo sapiens 53-56 35145497-3 2021 Retinoic acid-induced gene I-like receptor (RLRs) recognize virus RNA in virus infection, and LGP2 is a member of RLRs. Tretinoin 0-13 DExH-box helicase 58 Homo sapiens 94-98 34831243-5 2021 We show that primary liver cells sense RNA through retinoic acid-inducible gene I (RIG-I) like receptor (RLR) and Toll-like receptor 3 (TLR3) pathways. Tretinoin 51-64 DExH-box helicase 58 Homo sapiens 105-108 33605051-8 2021 Remarkably, the cleavage site on the RNA helicases MDA5 and LGP2, two relevant immune sensors of the retinoic acid-inducible gene-I (RIG-I)-like receptors family, resembles the L target site of Gemin5 and Daxx, and similar cleavage sites have been reported in ISG15 and TBK1, two proteins involved in type I interferon response and signaling pathway, respectively. Tretinoin 101-114 DExH-box helicase 58 Homo sapiens 60-64 30194441-1 2018 Retinoic acid-inducible gene I-like receptor (RLR) is one of the most important pattern recognition receptors of the innate immune system that detects positive and/or negative stranded RNA viruses. Tretinoin 0-13 DExH-box helicase 58 Homo sapiens 46-49 33241870-3 2021 The protein ankyrin repeat domain 17 (Ankrd17), a positive regulator of inflammatory responses via the retinoic acid-inducible gene-I (RIG-I)-like receptor (RLR) signaling pathway, was identified as a specific PA-X binding partner that preferred PA-X to the PA protein. Tretinoin 103-116 DExH-box helicase 58 Homo sapiens 157-160 32992291-3 2020 Previously studies by our group and others have confirmed that PDCoV nucleocapsid (N) protein performs an important role in antagonizing retinoic acid-induced gene I-like receptor (RLR) activation. Tretinoin 137-150 DExH-box helicase 58 Homo sapiens 164-185