PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10082969-4	1999	In density-arrested NRK cells, ET-1 and LPA induce phenotypic transformation rapidly, with similar kinetics as retinoic acid (RA) and transforming growth factor (TGF)-beta, while BK and PGF2alpha only do so with delayed kinetics.	Tretinoin	111-124	endothelin 1	Rattus norvegicus	31-35	
16619265-7	2006	AtRA also inhibited endothelin-1 (ET-1) expression in a time-dependent manner.	Tretinoin	0-4	endothelin 1	Rattus norvegicus	20-32	
16619265-7	2006	AtRA also inhibited endothelin-1 (ET-1) expression in a time-dependent manner.	Tretinoin	0-4	endothelin 1	Rattus norvegicus	34-38	
12813000-7	2003	In another set of experiments, cells treated for 10-12 days with vehicle (ethanol) or retinoic acid were challenged with ET-1 or sarafotoxin S6c, and various determinations were made at 24 h. 3 Retinoic acid inhibited transformation and proliferation of HSC as assessed by morphological characteristics, expression of alpha-sma, bromodeoxyuridine incorporation and cell count.	Tretinoin	194-207	endothelin 1	Rattus norvegicus	121-125	
12813000-11	2003	The presence of retinoic acid in the medium during treatment with ET-1 caused further reduction in the expression of alpha-smooth muscle actin.	Tretinoin	16-29	endothelin 1	Rattus norvegicus	66-70	
12813000-12	2003	ET-1 and sarafotoxin S6c stimulated total protein synthesis in vehicle- and retinoic acid-treated cells, but collagen synthesis only in the latter.	Tretinoin	76-89	endothelin 1	Rattus norvegicus	0-4	
10082969-4	1999	In density-arrested NRK cells, ET-1 and LPA induce phenotypic transformation rapidly, with similar kinetics as retinoic acid (RA) and transforming growth factor (TGF)-beta, while BK and PGF2alpha only do so with delayed kinetics.	Tretinoin	126-128	endothelin 1	Rattus norvegicus	31-35