PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33170091-7 2022 Intriguingly, rosiglitazone (RGZ) and hydroxychloroquine (HCQ) were found to be mild-to-moderate inhibitors of hAChE (human acetylcholinesterase) in our enzyme inhibition studies which are complementary to our computational studies. Hydroxychloroquine 38-56 acetylcholinesterase (Cartwright blood group) Homo sapiens 111-116 35411132-11 2022 Results: Molecular docking analysis revealed four putative key targets (ACHE, PNMT, MC1R, and VDR) of HCQ played important roles in vitiligo treatment. Hydroxychloroquine 102-105 acetylcholinesterase (Cartwright blood group) Homo sapiens 72-76 35411132-16 2022 The protective effects of HCQ are mediated by binding to putative targets ACHE, PNMT, MC1R, and VDR according to network pharmacology and docking verification. Hydroxychloroquine 26-29 acetylcholinesterase (Cartwright blood group) Homo sapiens 74-78 33170091-7 2022 Intriguingly, rosiglitazone (RGZ) and hydroxychloroquine (HCQ) were found to be mild-to-moderate inhibitors of hAChE (human acetylcholinesterase) in our enzyme inhibition studies which are complementary to our computational studies. Hydroxychloroquine 38-56 acetylcholinesterase (Cartwright blood group) Homo sapiens 124-144 33170091-7 2022 Intriguingly, rosiglitazone (RGZ) and hydroxychloroquine (HCQ) were found to be mild-to-moderate inhibitors of hAChE (human acetylcholinesterase) in our enzyme inhibition studies which are complementary to our computational studies. Hydroxychloroquine 58-61 acetylcholinesterase (Cartwright blood group) Homo sapiens 111-116 33170091-7 2022 Intriguingly, rosiglitazone (RGZ) and hydroxychloroquine (HCQ) were found to be mild-to-moderate inhibitors of hAChE (human acetylcholinesterase) in our enzyme inhibition studies which are complementary to our computational studies. Hydroxychloroquine 58-61 acetylcholinesterase (Cartwright blood group) Homo sapiens 124-144 33170091-8 2022 On the basis of our computational and experimental studies, it can be suggested that the beneficial effect of RGZ and HCQ in AD patients reported in the literature may partly be due to their AChE inhibitory property. Hydroxychloroquine 118-121 acetylcholinesterase (Cartwright blood group) Homo sapiens 191-195