PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3002400-10	1985	The short-lasting inhibitory effect of DDTC may be explained by its fast metabolic transformation into CS2, whereas the long-lasting effect of D is caused by its delayed degradation into this metabolite.	Ditiocarb	39-43	calsyntenin 2	Rattus norvegicus	103-106	
1311644-1	1992	The objective of this study was to determine whether the thiol drug, diethyldithiocarbamate (DEDC) and its two metabolites, disulfiram (DS) and carbon disulfide (CS2) could be used as inhibitors of cytochrome P-450IIE1 to protect hepatocytes from cytotoxic xenobiotics.	Ditiocarb	69-91	calsyntenin 2	Rattus norvegicus	162-165	
1311644-1	1992	The objective of this study was to determine whether the thiol drug, diethyldithiocarbamate (DEDC) and its two metabolites, disulfiram (DS) and carbon disulfide (CS2) could be used as inhibitors of cytochrome P-450IIE1 to protect hepatocytes from cytotoxic xenobiotics.	Ditiocarb	93-97	calsyntenin 2	Rattus norvegicus	162-165	
7529951-4	1995	The more toxic diethyldithiocarbamate had a short in vivo half-life, was oxidized to tetraethylthiuramdisulfide in blood, and was metabolized to high yields of CS2 in 24 h. In contrast, prolinedithiocarbamate was more stable in vivo, was found predominantly in the urinary tract and was excreted in urine.	Ditiocarb	15-37	calsyntenin 2	Rattus norvegicus	160-163	
9585486-9	1998	These results establish that CS2-mediated protein cross-linking occurs in vivo through the generation of Lys-Lys thiourea and that diethyldithiocarbamate can, through in vivo release of CS2, produce the same cross-linking structure.	Ditiocarb	131-153	calsyntenin 2	Rattus norvegicus	186-189