PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10543021-5	1999	Diethyldithiocarbamate, a CYP2E1 inhibitor, caused less inhibition of SO formation in Clara cells isolated from mice than previously found with pulmonary microsomes.	Ditiocarb	0-22	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	26-32	
22157718-3	2012	Some CCl(4)-intoxicated mice were also pretreated with the cytochrome P450 2E1 inhibitor diethyldithiocarbamate or the antioxidants Trolox C and dehydroepiandrosterone.	Ditiocarb	89-111	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	59-78	
17982890-0	2007	CYP 2E1 mutant mice are resistant to DDC-induced enhancement of MPTP toxicity.	Ditiocarb	37-40	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	0-7	
15447662-2	2004	In line with the enhancement of MPTP toxicity by diethyldithiocarbamate (DDC), here we demonstrate how other cytochrome P450 (CYP) 2E1 inhibitors, such as diallyl sulphide (DAS) and phenylethylisothiocyanate (PIC), also potentiate the selective DA neurone degeneration in C57/bl mice.	Ditiocarb	49-71	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	109-134	
15447662-2	2004	In line with the enhancement of MPTP toxicity by diethyldithiocarbamate (DDC), here we demonstrate how other cytochrome P450 (CYP) 2E1 inhibitors, such as diallyl sulphide (DAS) and phenylethylisothiocyanate (PIC), also potentiate the selective DA neurone degeneration in C57/bl mice.	Ditiocarb	73-76	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	109-134	
14980704-5	2004	The CYP1A2 inhibitor furafylline in vitro exacerbated microsomal H(2)O(2) production proportional to the degree of CYP1A2 inhibition, and the CYP2E1 inhibitor diethyldithiocarbamate decreased H(2)O(2) production proportional to the degree of CYP2E1 inhibition.	Ditiocarb	159-181	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	142-148	
14980704-5	2004	The CYP1A2 inhibitor furafylline in vitro exacerbated microsomal H(2)O(2) production proportional to the degree of CYP1A2 inhibition, and the CYP2E1 inhibitor diethyldithiocarbamate decreased H(2)O(2) production proportional to the degree of CYP2E1 inhibition.	Ditiocarb	159-181	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	242-248	
18583171-2	2008	Brain CYP2E1 inhibition by DDC in C57Bl mice was responsible for increased toxicity and striatal MPP(+) accumulation.	Ditiocarb	27-30	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	6-12	
17017526-5	2006	However, in these CYP 2E1 knockout mice, DDC pretreatment completely fails to enhance MPTP toxicity; this enhancement is instead regularly present in the SVI control animals.	Ditiocarb	41-44	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	18-25	
12204549-6	2002	Prior treatment with either diethyldithiocarbamate or 5-phenyl-1-pentyne as inhibitors of CYP2E1 and CYP2F2 prevented or greatly decreased the hepatotoxicity of 4-VP as assessed by measuring serum sorbitol dehydrogenase and its pneumotoxicity as determined by measurements of cells, protein and lactate dehydrogenase (LDH) activity in bronchoalveolar lavage fluid.	Ditiocarb	28-50	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	90-96	
9233381-10	1997	Addition of the CYP2E1 inhibitor diethyldithiocarbamate decreased the formation of both enantiomers in both tissues from control mice, whereas 5-phenyl-1-pentyne (an inhibitor of CYP2F2) inhibited metabolism primarily in lung.	Ditiocarb	33-55	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	16-22