PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27412967-2	2016	We previously demonstrated that diethyldithiocarbamate (DDC) up-regulates MMP-1 in hepatic stellate cells via the ERK1/2 and Akt signalling pathways.	Ditiocarb	32-54	mitogen-activated protein kinase 3	Homo sapiens	114-120	
27412967-2	2016	We previously demonstrated that diethyldithiocarbamate (DDC) up-regulates MMP-1 in hepatic stellate cells via the ERK1/2 and Akt signalling pathways.	Ditiocarb	56-59	mitogen-activated protein kinase 3	Homo sapiens	114-120	
23577625-0	2013	The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism.	Ditiocarb	21-24	mitogen-activated protein kinase 3	Homo sapiens	88-94	
23577625-7	2013	ERK1/2 (extracellular signal-regulated kinase 1/2), Akt (protein kinase B) and p38 were significantly activated by DDC.	Ditiocarb	115-118	mitogen-activated protein kinase 3	Homo sapiens	0-6	
23577625-8	2013	The ERK1/2 inhibitor (U0126) and Akt inhibitor (T3830) abrogated the DDC-induced MMP-1 up-regulation.	Ditiocarb	69-72	mitogen-activated protein kinase 3	Homo sapiens	4-10	
23577625-11	2013	The enhancement of MMP-1 expression by DDC was associated with H2O2 inhibition and coordinated regulation by the ERK1/2 and Akt pathways.	Ditiocarb	39-42	mitogen-activated protein kinase 3	Homo sapiens	113-119	
17205976-10	2007	The ROS formation was inhibited by the extracellular signal-regulated protein kinase (ERK) inhibitor U0126 (10 microM), the tyrosine kinase inhibitor erbstatin-A (25 microM), eliminating calcium from the buffer and by the superoxide dismutase inhibitor diethyldithio-carbamic acid (DDC, 100 microM).	Ditiocarb	253-280	mitogen-activated protein kinase 3	Homo sapiens	86-89