PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23577625-0 2013 The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism. Ditiocarb 21-24 mitogen-activated protein kinase 3 Homo sapiens 88-94 23577625-7 2013 ERK1/2 (extracellular signal-regulated kinase 1/2), Akt (protein kinase B) and p38 were significantly activated by DDC. Ditiocarb 115-118 mitogen-activated protein kinase 3 Homo sapiens 0-6 23577625-8 2013 The ERK1/2 inhibitor (U0126) and Akt inhibitor (T3830) abrogated the DDC-induced MMP-1 up-regulation. Ditiocarb 69-72 mitogen-activated protein kinase 3 Homo sapiens 4-10 23577625-11 2013 The enhancement of MMP-1 expression by DDC was associated with H2O2 inhibition and coordinated regulation by the ERK1/2 and Akt pathways. Ditiocarb 39-42 mitogen-activated protein kinase 3 Homo sapiens 113-119 27412967-2 2016 We previously demonstrated that diethyldithiocarbamate (DDC) up-regulates MMP-1 in hepatic stellate cells via the ERK1/2 and Akt signalling pathways. Ditiocarb 32-54 mitogen-activated protein kinase 3 Homo sapiens 114-120 27412967-2 2016 We previously demonstrated that diethyldithiocarbamate (DDC) up-regulates MMP-1 in hepatic stellate cells via the ERK1/2 and Akt signalling pathways. Ditiocarb 56-59 mitogen-activated protein kinase 3 Homo sapiens 114-120 17205976-10 2007 The ROS formation was inhibited by the extracellular signal-regulated protein kinase (ERK) inhibitor U0126 (10 microM), the tyrosine kinase inhibitor erbstatin-A (25 microM), eliminating calcium from the buffer and by the superoxide dismutase inhibitor diethyldithio-carbamic acid (DDC, 100 microM). Ditiocarb 253-280 mitogen-activated protein kinase 3 Homo sapiens 86-89