PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1495979-3	1992	The processing of bET to all its metabolites including ET-1 was prevented by the serine protease inhibitor 3,4-dichloroisocoumarin (DCI; 50 microM) or the elastase inhibitor ONO-5046 (100 microM) but not by phenylmethylsulfonyl fluoride (PMSF; 143 microM), another serine protease inhibitor.	3,4-dichloroisocoumarin	107-130	endothelin 1	Homo sapiens	55-59	
1495979-3	1992	The processing of bET to all its metabolites including ET-1 was prevented by the serine protease inhibitor 3,4-dichloroisocoumarin (DCI; 50 microM) or the elastase inhibitor ONO-5046 (100 microM) but not by phenylmethylsulfonyl fluoride (PMSF; 143 microM), another serine protease inhibitor.	3,4-dichloroisocoumarin	132-135	endothelin 1	Homo sapiens	55-59	
1495979-6	1992	The generation of ET-1 following this intervention was inhibited by DCI.	3,4-dichloroisocoumarin	68-71	endothelin 1	Homo sapiens	18-22	
1495979-8	1992	The degradation of ET-1 by PMN microsomes was prevented by DCI, PMSF, or ONO-5046.	3,4-dichloroisocoumarin	59-62	endothelin 1	Homo sapiens	19-23	
1282976-2	1992	Either the general serine protease inhibitor 3,4-dichloroisocoumarin (DCI; 50 microM) or the selective elastase inhibitor ONO-5046 (100 microM) blocked the formation of ET-1 from bET-1.	3,4-dichloroisocoumarin	45-68	endothelin 1	Homo sapiens	169-173	
1282976-2	1992	Either the general serine protease inhibitor 3,4-dichloroisocoumarin (DCI; 50 microM) or the selective elastase inhibitor ONO-5046 (100 microM) blocked the formation of ET-1 from bET-1.	3,4-dichloroisocoumarin	70-73	endothelin 1	Homo sapiens	169-173