PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12040027-0	2002	Potential role of nuclear factor kappaB and reactive oxygen species in cAMP and cytokine regulation of surfactant protein-A gene expression in lung type II cells.	Reactive Oxygen Species	44-67	surfactant protein A1	Homo sapiens	103-123	
25078973-6	2014	SP-A and SP-B induced apoptosis was accompanied by significant increase in the formation of intracellular reactive oxygen species (ROS).	Reactive Oxygen Species	106-129	surfactant protein A1	Homo sapiens	0-4	
25078973-6	2014	SP-A and SP-B induced apoptosis was accompanied by significant increase in the formation of intracellular reactive oxygen species (ROS).	Reactive Oxygen Species	131-134	surfactant protein A1	Homo sapiens	0-4	
25078973-7	2014	Pre-treatment with N-acetyl-l-cysteine (NAC), significantly inhibited the SP-A and SP-B mediated apoptosis, suggesting a vital role of ROS involved in the lethality of both agents.	Reactive Oxygen Species	135-138	surfactant protein A1	Homo sapiens	74-78	
25078973-10	2014	In this study, we suggest that a marked induction of intracellular ROS mediated mitochondrial pathway and the Fas plays a role in the SP-A and SP-B induced apoptosis.	Reactive Oxygen Species	67-70	surfactant protein A1	Homo sapiens	134-138	
8198539-4	1994	Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.	Reactive Oxygen Species	46-60	surfactant protein A1	Homo sapiens	14-18	
9777404-8	1998	SP-A and SP-D stimulate chemotaxis of phagocytes and once bound to the phagocytes, the production of oxygen radicals can be induced.	Reactive Oxygen Species	101-116	surfactant protein A1	Homo sapiens	0-4	
7828630-4	1994	Such binding effects the release of reactive oxygen species from resident alveolar macrophages if SP-A is properly presented to the target cell.	Reactive Oxygen Species	36-59	surfactant protein A1	Homo sapiens	98-102	
31449845-0	2019	Adverse impact of ambient PM2.5 on expression and trafficking of surfactant protein A through reactive oxygen species damage to lamellar bodies.	Reactive Oxygen Species	94-117	surfactant protein A1	Homo sapiens	65-85	
32780286-13	2021	Moreover, novel non-ROS-related proteins were part of these forming functional hybrids, such as the NOX5/sGC, NOX1,2/NOS2, NRF2/ENC-1 and MPO/SP-A modules.	Reactive Oxygen Species	20-23	surfactant protein A1	Homo sapiens	142-146	
32933785-0	2020	Corrigendum to "Adverse impact of ambient PM2.5 on expression and trafficking of surfactant protein A through reactive oxygen species damage to lamellar bodies" [Toxicology Letters 315 (2019) 47-54].	Reactive Oxygen Species	110-133	surfactant protein A1	Homo sapiens	81-101	
30651822-8	2019	Compared with the control group, SP-A treatment significantly increased the ROS production, type I collagen secretion and cell apoptosis, which was partially inhibited by addition of anti-CRT.	Reactive Oxygen Species	76-79	surfactant protein A1	Homo sapiens	33-37