PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34074012-5	2021	Moreover, several studies have highlighted how the age-related alteration of reactive oxygen species (ROS) homeostasis can contribute to changes in the neuromuscular junction morphology and stability, leading to the reduction in fiber number and innervation.	Reactive Oxygen Species	77-100	renin binding protein	Homo sapiens	51-54	
34074012-5	2021	Moreover, several studies have highlighted how the age-related alteration of reactive oxygen species (ROS) homeostasis can contribute to changes in the neuromuscular junction morphology and stability, leading to the reduction in fiber number and innervation.	Reactive Oxygen Species	102-105	renin binding protein	Homo sapiens	51-54	
34990649-0	2022	Indole-linked 1,2,3-triazole derivatives efficiently modulate COX-2 protein levels in human THP-1 monocytes by suppressing AGE-ROS-NF-kbeta nexus.	Reactive Oxygen Species	127-130	renin binding protein	Homo sapiens	123-126	
33781808-6	2021	vRAGE-ELP reversed several AGE-mediated changes in cultured human umbilical vein endothelial cells, including a decrease in viable cell number, an increase in levels of reactive oxygen species (ROS), and an increased expression of the pro-inflammatory marker, intercellular adhesion molecule-1 (ICAM-1).	Reactive Oxygen Species	169-192	renin binding protein	Homo sapiens	2-5	
33781808-6	2021	vRAGE-ELP reversed several AGE-mediated changes in cultured human umbilical vein endothelial cells, including a decrease in viable cell number, an increase in levels of reactive oxygen species (ROS), and an increased expression of the pro-inflammatory marker, intercellular adhesion molecule-1 (ICAM-1).	Reactive Oxygen Species	194-197	renin binding protein	Homo sapiens	2-5	
30714539-6	2019	OBJECTIVE: We proposed that age, obesity and mtDNA deletion are three ROS producing factors, which may interact with each other and induce senescence.	Reactive Oxygen Species	70-73	renin binding protein	Homo sapiens	28-31	
33359687-4	2021	Here, we comprehensively investigate age-related accumulation of AGEs and dicarbonyls, including methylglyoxal (MG), glyoxal (GO), and 3-deoxyglucosone (3-DG), and the effects of mitochondrial reactive oxygen species (ROS) on cerebral AGEs accumulation, mitochondrial function, and oxidative stress in the aging human and mouse brain.	Reactive Oxygen Species	193-216	renin binding protein	Homo sapiens	37-40	
33359687-4	2021	Here, we comprehensively investigate age-related accumulation of AGEs and dicarbonyls, including methylglyoxal (MG), glyoxal (GO), and 3-deoxyglucosone (3-DG), and the effects of mitochondrial reactive oxygen species (ROS) on cerebral AGEs accumulation, mitochondrial function, and oxidative stress in the aging human and mouse brain.	Reactive Oxygen Species	218-221	renin binding protein	Homo sapiens	37-40	
33261212-4	2020	AGEs, by binding to receptors for AGE (RAGEs), alter innate and adaptive immune responses to induce inflammation and immunosuppression via the generation of proinflammatory cytokines, reactive oxygen species (ROS), and reactive nitrogen intermediates (RNI).	Reactive Oxygen Species	184-207	renin binding protein	Homo sapiens	0-3	
33261212-4	2020	AGEs, by binding to receptors for AGE (RAGEs), alter innate and adaptive immune responses to induce inflammation and immunosuppression via the generation of proinflammatory cytokines, reactive oxygen species (ROS), and reactive nitrogen intermediates (RNI).	Reactive Oxygen Species	209-212	renin binding protein	Homo sapiens	0-3	
31375034-11	2019	Moreover, Fruc-AGE-aptamer prevented the Fruc-AGE- and fructose-induced reactive oxygen species generation and vascular cell adhesion molecule-1 gene expression in human umbilical vein endothelial cells.	Reactive Oxygen Species	72-95	renin binding protein	Homo sapiens	15-18	
31375034-11	2019	Moreover, Fruc-AGE-aptamer prevented the Fruc-AGE- and fructose-induced reactive oxygen species generation and vascular cell adhesion molecule-1 gene expression in human umbilical vein endothelial cells.	Reactive Oxygen Species	72-95	renin binding protein	Homo sapiens	46-49	
31079281-4	2019	AGE and its interaction with RAGE-mediated increase in the reactive oxygen species (ROS) damage brain because of its increased vulnerability to ROS.	Reactive Oxygen Species	59-82	renin binding protein	Homo sapiens	0-3	
31079281-4	2019	AGE and its interaction with RAGE-mediated increase in the reactive oxygen species (ROS) damage brain because of its increased vulnerability to ROS.	Reactive Oxygen Species	84-87	renin binding protein	Homo sapiens	0-3	
31079281-4	2019	AGE and its interaction with RAGE-mediated increase in the reactive oxygen species (ROS) damage brain because of its increased vulnerability to ROS.	Reactive Oxygen Species	144-147	renin binding protein	Homo sapiens	0-3	
27451257-2	2016	In order to attenuate the progression of AD, we designed a new type of molecules that consist of two trapping parts for reactive carbonyl species (RCS) and reactive oxygen species (ROS), precursors of AGE and ALE, respectively.	Reactive Oxygen Species	156-179	renin binding protein	Homo sapiens	201-204	
27451257-2	2016	In order to attenuate the progression of AD, we designed a new type of molecules that consist of two trapping parts for reactive carbonyl species (RCS) and reactive oxygen species (ROS), precursors of AGE and ALE, respectively.	Reactive Oxygen Species	181-184	renin binding protein	Homo sapiens	201-204