PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34681943-9 2021 These effects are mediated via ROS generation and changes in gene expression, including upregulation of Wnt/beta-catenin pathway antagonists, SFRP1, and RUNX3, and downregulation of UHRF1, the key epigenetic regulator. Reactive Oxygen Species 31-34 secreted frizzled related protein 1 Homo sapiens 142-147