PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35223993-0 2022 ROS-Induced DCTPP1 Upregulation Contributes to Cisplatin Resistance in Ovarian Cancer. Reactive Oxygen Species 0-3 dCTP pyrophosphatase 1 Homo sapiens 12-18 35223993-5 2022 Our results indicates cisplatin-induced ROS generation was responsible for the upregulation of DCTPP1 in ovarian cancer cells, whereas DCTPP1 knockdown significantly enhanced the sensitivity of ovarian cancer cells to cisplatin, reflect in reactive oxygen species (ROS) generation, double-strand DNA breaks, and cell apoptosis. Reactive Oxygen Species 40-43 dCTP pyrophosphatase 1 Homo sapiens 95-101 35223993-5 2022 Our results indicates cisplatin-induced ROS generation was responsible for the upregulation of DCTPP1 in ovarian cancer cells, whereas DCTPP1 knockdown significantly enhanced the sensitivity of ovarian cancer cells to cisplatin, reflect in reactive oxygen species (ROS) generation, double-strand DNA breaks, and cell apoptosis. Reactive Oxygen Species 240-263 dCTP pyrophosphatase 1 Homo sapiens 95-101 35223993-5 2022 Our results indicates cisplatin-induced ROS generation was responsible for the upregulation of DCTPP1 in ovarian cancer cells, whereas DCTPP1 knockdown significantly enhanced the sensitivity of ovarian cancer cells to cisplatin, reflect in reactive oxygen species (ROS) generation, double-strand DNA breaks, and cell apoptosis. Reactive Oxygen Species 240-263 dCTP pyrophosphatase 1 Homo sapiens 135-141 35223993-5 2022 Our results indicates cisplatin-induced ROS generation was responsible for the upregulation of DCTPP1 in ovarian cancer cells, whereas DCTPP1 knockdown significantly enhanced the sensitivity of ovarian cancer cells to cisplatin, reflect in reactive oxygen species (ROS) generation, double-strand DNA breaks, and cell apoptosis. Reactive Oxygen Species 265-268 dCTP pyrophosphatase 1 Homo sapiens 95-101 35223993-5 2022 Our results indicates cisplatin-induced ROS generation was responsible for the upregulation of DCTPP1 in ovarian cancer cells, whereas DCTPP1 knockdown significantly enhanced the sensitivity of ovarian cancer cells to cisplatin, reflect in reactive oxygen species (ROS) generation, double-strand DNA breaks, and cell apoptosis. Reactive Oxygen Species 265-268 dCTP pyrophosphatase 1 Homo sapiens 135-141