PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28511187-6 2017 We found that Epo protects Ast from H2O2 injury (p < 0.05) and increases secreted nitric oxide levels in these cells (p < 0.05) while suppressing intracellular reactive oxygen species (p < 0.05) and superoxide ion (p < 0.05) levels only in Mg. Reactive Oxygen Species 166-189 erythropoietin Mus musculus 14-17 19679834-9 2009 In cultured EPCs from WT but not Nox2(y/-) mice, EPO induced ROS production, migration, and proliferation. Reactive Oxygen Species 61-64 erythropoietin Mus musculus 49-52 15982852-2 2006 Here we demonstrate that IL-3 or Epo induces a rapid and transient (peaking at 30 min) as well as late progressive increase in reactive oxygen species (ROS) in a hematopoietic progenitor model cell line, 32Dcl3, and its subclone expressing the Epo receptor (EpoR), 32D/EpoR-Wt. Reactive Oxygen Species 127-150 erythropoietin Mus musculus 33-36 16288465-10 2006 Our study demonstrates an important role for Epo in the protection of astrocytes from reactive oxygen species. Reactive Oxygen Species 86-109 erythropoietin Mus musculus 45-48 17928571-7 2008 DOX-mediated increases in reactive oxygen species, which trigger cardiotoxicity, were also reversed by preconditioning with EPO. Reactive Oxygen Species 26-49 erythropoietin Mus musculus 124-127 17174578-6 2007 These results suggest that reactive oxygen species are involved in Epo-mediated erythroid differentiation. Reactive Oxygen Species 27-50 erythropoietin Mus musculus 67-70 15982852-2 2006 Here we demonstrate that IL-3 or Epo induces a rapid and transient (peaking at 30 min) as well as late progressive increase in reactive oxygen species (ROS) in a hematopoietic progenitor model cell line, 32Dcl3, and its subclone expressing the Epo receptor (EpoR), 32D/EpoR-Wt. Reactive Oxygen Species 152-155 erythropoietin Mus musculus 33-36 15890996-11 2005 CONCLUSIONS: Hypoxic preconditioning induces ROS, which may downregulate the threshold for production of HIF-1alpha and Epo expression during subsequent lethal hypoxia, thus exerting neuroprotection through the Jak2-Stat5 and NF-kappaB pathways. Reactive Oxygen Species 45-48 erythropoietin Mus musculus 120-123 33942716-5 2021 Mechanistically, EPO production is impaired in REPs in Fundc1-/- mice upon stresses, and the impairment is caused by the accumulation of damaged mitochondria, which consequently leads to the elevation of the reactive oxygen species (ROS) level and triggers inflammatory responses by up-regulating proinflammatory cytokines. Reactive Oxygen Species 208-231 erythropoietin Mus musculus 17-20 33942716-5 2021 Mechanistically, EPO production is impaired in REPs in Fundc1-/- mice upon stresses, and the impairment is caused by the accumulation of damaged mitochondria, which consequently leads to the elevation of the reactive oxygen species (ROS) level and triggers inflammatory responses by up-regulating proinflammatory cytokines. Reactive Oxygen Species 233-236 erythropoietin Mus musculus 17-20