PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11563880-1 2001 Vascular cell adhesion molecule-1 (VCAM-1) activates endothelial cell NADPH oxidase which catalyzes production of reactive oxygen species (ROS). Reactive Oxygen Species 114-137 vascular cell adhesion molecule 1 Mus musculus 0-33 11911350-8 2002 These data suggest that reactive oxygen species produced in response to BDL may up-regulate VCAM-1 expression in the lung and play an important role in the pathophysiology of this pulmonary injury. Reactive Oxygen Species 24-47 vascular cell adhesion molecule 1 Mus musculus 92-98 11563880-1 2001 Vascular cell adhesion molecule-1 (VCAM-1) activates endothelial cell NADPH oxidase which catalyzes production of reactive oxygen species (ROS). Reactive Oxygen Species 114-137 vascular cell adhesion molecule 1 Mus musculus 35-41 11563880-1 2001 Vascular cell adhesion molecule-1 (VCAM-1) activates endothelial cell NADPH oxidase which catalyzes production of reactive oxygen species (ROS). Reactive Oxygen Species 139-142 vascular cell adhesion molecule 1 Mus musculus 0-33 11563880-1 2001 Vascular cell adhesion molecule-1 (VCAM-1) activates endothelial cell NADPH oxidase which catalyzes production of reactive oxygen species (ROS). Reactive Oxygen Species 139-142 vascular cell adhesion molecule 1 Mus musculus 35-41 11563880-7 2001 TGF-beta1 and IFN-gamma blocked migration by inhibiting the VCAM-1-stimulated production of low levels of ROS (0.1-0.9 microM H2O2). Reactive Oxygen Species 106-109 vascular cell adhesion molecule 1 Mus musculus 60-66 33763173-0 2021 Detection of Vascular Reactive Oxygen Species in Experimental Atherosclerosis by High-Resolution Near-Infrared Fluorescence Imaging Using VCAM-1-Targeted Liposomes Entrapping a Fluorogenic Redox-Sensitive Probe. Reactive Oxygen Species 22-45 vascular cell adhesion molecule 1 Mus musculus 138-144 10843714-8 2000 Furthermore, VCAM-1 ligand binding stimulated NADPH oxidase-dependent production of ROS by the endothelial cells lines and primary endothelial cell cultures. Reactive Oxygen Species 84-87 vascular cell adhesion molecule 1 Mus musculus 13-19 33763173-4 2021 To this purpose, the cell-impermeant ROS Brite 700 (RB700) probe that produces bright near-infrared fluorescence upon ROS oxidation was encapsulated into VCAM-1-targeted, sterically stabilized liposomes (VLp). Reactive Oxygen Species 37-40 vascular cell adhesion molecule 1 Mus musculus 155-161 33763173-4 2021 To this purpose, the cell-impermeant ROS Brite 700 (RB700) probe that produces bright near-infrared fluorescence upon ROS oxidation was encapsulated into VCAM-1-targeted, sterically stabilized liposomes (VLp). Reactive Oxygen Species 119-122 vascular cell adhesion molecule 1 Mus musculus 155-161 33763173-12 2021 RB700 encapsulation into sterically stabilized VCAM-1-sensitive Lp could be a novel strategy for the qualitative and quantitative detection of ROS in the vasculature and various organs and tissues in animal models of disease. Reactive Oxygen Species 143-146 vascular cell adhesion molecule 1 Mus musculus 47-53 28365565-4 2017 A potent antioxidant, bilirubin effectively blocks the generation of cellular reactive oxygen species induced by the cross-linking of endothelial vascular cell adhesion molecule 1 (VCAM-1) or intercellular adhesion molecule 1 (ICAM-1). Reactive Oxygen Species 78-101 vascular cell adhesion molecule 1 Mus musculus 146-179 29861828-5 2018 The results from the cell model showed that pretreatment of HUVEC with the water or alkaline extracts of the polysaccharides from the huskless barley cultivars QHH and NLGL decreased the levels of reactive oxygen species (ROS), monocyte chemotactic protein 1 (MCP-1), and vascular cell adhesion molecule 1 (VCAM-1) but increased the level of superoxide dismutase (SOD) and maintained cell viability. Reactive Oxygen Species 197-220 vascular cell adhesion molecule 1 Mus musculus 272-305 29861828-5 2018 The results from the cell model showed that pretreatment of HUVEC with the water or alkaline extracts of the polysaccharides from the huskless barley cultivars QHH and NLGL decreased the levels of reactive oxygen species (ROS), monocyte chemotactic protein 1 (MCP-1), and vascular cell adhesion molecule 1 (VCAM-1) but increased the level of superoxide dismutase (SOD) and maintained cell viability. Reactive Oxygen Species 197-220 vascular cell adhesion molecule 1 Mus musculus 307-313 28365565-4 2017 A potent antioxidant, bilirubin effectively blocks the generation of cellular reactive oxygen species induced by the cross-linking of endothelial vascular cell adhesion molecule 1 (VCAM-1) or intercellular adhesion molecule 1 (ICAM-1). Reactive Oxygen Species 78-101 vascular cell adhesion molecule 1 Mus musculus 181-187 19797522-6 2010 This early association is dependent on reactive oxygen species (ROS) partly through the regulation of vascular cell adhesion molecule-1 expression on endothelial cells and is followed by a ROS-dependent proliferation of LSKCD34(-) hematopoietic cells. Reactive Oxygen Species 39-62 vascular cell adhesion molecule 1 Mus musculus 102-135 21372295-8 2011 Lysophosphatidylcholine-activated PYK2 induced NADPH oxidase-mediated ROS generation and ROS-mediated synthesis of tumor necrosis factor-alpha (TNFalpha), vascular cell adhesion molecule-1 (VCAM-1), monocyte chemotactic protein-1 (MCP-1), and p21Cip1/Ets-1. Reactive Oxygen Species 89-92 vascular cell adhesion molecule 1 Mus musculus 155-188 21372295-8 2011 Lysophosphatidylcholine-activated PYK2 induced NADPH oxidase-mediated ROS generation and ROS-mediated synthesis of tumor necrosis factor-alpha (TNFalpha), vascular cell adhesion molecule-1 (VCAM-1), monocyte chemotactic protein-1 (MCP-1), and p21Cip1/Ets-1. Reactive Oxygen Species 89-92 vascular cell adhesion molecule 1 Mus musculus 190-196 20876216-1 2011 Elevated generation of reactive oxygen species (ROS) by endothelial enzymes, including NADPH-oxidase, is implicated in vascular oxidative stress and endothelial proinflammatory activation involving exposure of vascular cell adhesion molecule-1 (VCAM-1). Reactive Oxygen Species 23-46 vascular cell adhesion molecule 1 Mus musculus 210-243 20876216-1 2011 Elevated generation of reactive oxygen species (ROS) by endothelial enzymes, including NADPH-oxidase, is implicated in vascular oxidative stress and endothelial proinflammatory activation involving exposure of vascular cell adhesion molecule-1 (VCAM-1). Reactive Oxygen Species 23-46 vascular cell adhesion molecule 1 Mus musculus 245-251 20876216-1 2011 Elevated generation of reactive oxygen species (ROS) by endothelial enzymes, including NADPH-oxidase, is implicated in vascular oxidative stress and endothelial proinflammatory activation involving exposure of vascular cell adhesion molecule-1 (VCAM-1). Reactive Oxygen Species 48-51 vascular cell adhesion molecule 1 Mus musculus 210-243 20876216-1 2011 Elevated generation of reactive oxygen species (ROS) by endothelial enzymes, including NADPH-oxidase, is implicated in vascular oxidative stress and endothelial proinflammatory activation involving exposure of vascular cell adhesion molecule-1 (VCAM-1). Reactive Oxygen Species 48-51 vascular cell adhesion molecule 1 Mus musculus 245-251 23181590-0 2013 The role of ROS in ionizing radiation-induced VLA-4 mediated adhesion of RAW264.7 cells to VCAM-1 under flow conditions. Reactive Oxygen Species 12-15 vascular cell adhesion molecule 1 Mus musculus 91-97 19448154-6 2010 Further analysis, aimed at identifying mediators downstream of BLT2, revealed that BLT2 activation led to elevation of reactive oxygen species and subsequent activation of NF-kappaB, thus inducing the expression of vascular cell adhesion molecule-1, which is known to be involved in eosinophil infiltration into the lung airway. Reactive Oxygen Species 119-142 vascular cell adhesion molecule 1 Mus musculus 215-248 19797522-6 2010 This early association is dependent on reactive oxygen species (ROS) partly through the regulation of vascular cell adhesion molecule-1 expression on endothelial cells and is followed by a ROS-dependent proliferation of LSKCD34(-) hematopoietic cells. Reactive Oxygen Species 64-67 vascular cell adhesion molecule 1 Mus musculus 102-135 19797522-6 2010 This early association is dependent on reactive oxygen species (ROS) partly through the regulation of vascular cell adhesion molecule-1 expression on endothelial cells and is followed by a ROS-dependent proliferation of LSKCD34(-) hematopoietic cells. Reactive Oxygen Species 189-192 vascular cell adhesion molecule 1 Mus musculus 102-135 19874473-9 2010 Expression of TNF-alpha-induced intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 was inhibited by K(1-5) treatment, possibly via downregulation of translocation of nuclear factor-kappaB and expression of reactive oxygen species. Reactive Oxygen Species 227-250 vascular cell adhesion molecule 1 Mus musculus 70-103 15749910-1 2005 UNLABELLED: During lymphocyte migration, engagement of VCAM-1 stimulates the generation of endothelial cell-derived reactive oxygen species (ROS) and activation of matrix metalloproteinases, facilitating endothelial retraction. Reactive Oxygen Species 116-139 vascular cell adhesion molecule 1 Mus musculus 55-61 15749910-1 2005 UNLABELLED: During lymphocyte migration, engagement of VCAM-1 stimulates the generation of endothelial cell-derived reactive oxygen species (ROS) and activation of matrix metalloproteinases, facilitating endothelial retraction. Reactive Oxygen Species 141-144 vascular cell adhesion molecule 1 Mus musculus 55-61 15749910-4 2005 Bilirubin administration also suppresses VCAM-1-stimulated ROS generation and reduces endothelial cell matrix metalloproteinase activity. Reactive Oxygen Species 59-62 vascular cell adhesion molecule 1 Mus musculus 41-47