PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34149998-0	2021	SYVN1/GPX5 axis affects ischemia/reperfusion induced apoptosis of AC16 cells by regulating ROS generation.	Reactive Oxygen Species	91-94	synoviolin 1	Homo sapiens	0-5	
34149998-8	2021	In I/R-induced AC16 cells, the expression of SYVN1 was up-regulated, and SYVN1 knock-down decreased the ROS levels and apoptotic rate but increased GPX5 levels.	Reactive Oxygen Species	104-107	synoviolin 1	Homo sapiens	73-78	
34149998-9	2021	Moreover, GPX5 knockdown promoted ROS production and apoptosis, while its effects were attenuated by SYVN1 knockdown.	Reactive Oxygen Species	34-37	synoviolin 1	Homo sapiens	101-106	
31322186-9	2019	Notably, overexpression of Hrd1 abolished the protective effect of ATRA on the UV-induced decrease of Nrf2 expression, the production of reactive oxygen species (ROS) and the decrease of cell viability.	Reactive Oxygen Species	137-160	synoviolin 1	Homo sapiens	27-31	
31322186-9	2019	Notably, overexpression of Hrd1 abolished the protective effect of ATRA on the UV-induced decrease of Nrf2 expression, the production of reactive oxygen species (ROS) and the decrease of cell viability.	Reactive Oxygen Species	162-165	synoviolin 1	Homo sapiens	27-31