PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21909943-5	2011	In accordance with previous results in breast cancer cells (Choi et al., 2010), the knockdown of GIPC reduced ROS production in response to IGF-1 in colon cancer cells.	Reactive Oxygen Species	110-113	GIPC PDZ domain containing family member 1	Homo sapiens	97-101	
21909943-7	2011	Taken together, these data suggest that GIPC is involved in IGF-1 signaling leading to ZNF143 expression through the regulation of ROS production, which may play a role for colon cancer tumorigenesis.	Reactive Oxygen Species	131-134	GIPC PDZ domain containing family member 1	Homo sapiens	40-44	
20206441-0	2010	GIPC mediates the generation of reactive oxygen species and the regulation of cancer cell proliferation by insulin-like growth factor-1/IGF-1R signaling.	Reactive Oxygen Species	32-55	GIPC PDZ domain containing family member 1	Homo sapiens	0-4	
20206441-6	2010	siRNA-mediated silencing of GIPC expression also decreased IGF-1-mediated reactive oxygen species generation.	Reactive Oxygen Species	74-97	GIPC PDZ domain containing family member 1	Homo sapiens	28-32	
20206441-7	2010	Taken together, these data suggest that GIPC contributes to IGF-1-induced cancer cell proliferation via the regulation of reactive oxygen species production.	Reactive Oxygen Species	122-145	GIPC PDZ domain containing family member 1	Homo sapiens	40-44