PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32910941-5	2020	Interrupting the E2F1/HMGA1/G6PD regulatory axis increased reactive oxygen species (ROS) levels, DNA damage, and apoptosis in RPE cells under oxidative stress.	Reactive Oxygen Species	59-82	high mobility group AT-hook 1	Homo sapiens	22-27	
32910941-5	2020	Interrupting the E2F1/HMGA1/G6PD regulatory axis increased reactive oxygen species (ROS) levels, DNA damage, and apoptosis in RPE cells under oxidative stress.	Reactive Oxygen Species	84-87	high mobility group AT-hook 1	Homo sapiens	22-27	
31476307-2	2019	The present report was premeditated to uncover the regulatory role of HMG-R inhibitors and ezetimibe (EZ) in attenuating the LDL-AGEs-induced pathogenicity via targeting cellular-ROS and RAGE-associated signalling in HEK-293 cells.	Reactive Oxygen Species	179-182	high mobility group AT-hook 1	Homo sapiens	70-75	
31476307-9	2019	SIGNIFICANCE: The above pharmacological effects signify that HMG-R inhibitors and EZ (alone or in combination) may implied in the treatment of AGEs-induced oxidative stress and tissue damage in diabetic complications via targeting intracellular-ROS, NRP-1 functionality and RAGE-associated genes i.e. NF-kappaB, TGFbeta-1, and MMP-2.	Reactive Oxygen Species	245-248	high mobility group AT-hook 1	Homo sapiens	61-66	
19687300-7	2009	Additionally, the level of cellular reactive oxygen species (ROS) increased and the efficiency of repair of oxidatively damaged mtDNA decreased as consequences of elevated HMGA1 expression.	Reactive Oxygen Species	36-59	high mobility group AT-hook 1	Homo sapiens	172-177	
19687300-7	2009	Additionally, the level of cellular reactive oxygen species (ROS) increased and the efficiency of repair of oxidatively damaged mtDNA decreased as consequences of elevated HMGA1 expression.	Reactive Oxygen Species	61-64	high mobility group AT-hook 1	Homo sapiens	172-177	
19687300-8	2009	Increased ROS levels and reduced repair efficiency in HMGA1-overexpressing cells likely contribute to the increased occurrence of mutations in mtDNA frequently observed in cancer cells.	Reactive Oxygen Species	10-13	high mobility group AT-hook 1	Homo sapiens	54-59