PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28402042-12 2017 The clinicopathological findings of the present case confirm several hypotheses: (i) the earliest pathologic evidence observed by HE staining in CJD are spongiform changes; (ii) DWI hyperintense regions indicate these spongiform changes; and (iii) regions without spongiform changes, gliosis and proliferation of GFAP-positive astrocytes, but with PrP deposition, exist in the early disease stage. Helium 130-132 prion protein Homo sapiens 348-351 32248827-14 2020 H&E staining and toluidine blue staining of the cartilage exhibited an obvious amelioration of inflammation and cartilage matrix loss after being treated with P-PRP for both groups, especially the mild group. Helium 0-3 prion protein Homo sapiens 161-164