PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32952955-12	2020	Meanwhile, ginkgolide B reduced Levels of p-P38, and p-JNK, and increased levels of p-PI3K and p-Akt.	Ginkgolides	11-21	AKT serine/threonine kinase 1	Rattus norvegicus	97-100	
29542683-0	2018	Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling.	Ginkgolides	10-21	AKT serine/threonine kinase 1	Rattus norvegicus	124-127	
29542683-10	2018	These observations suggest that ginkgolides act as novel extrinsic regulators activating both Akt/Nrf2 and Akt/CREB signaling pathways, protecting against cerebral ischemia/reperfusion (I/R) damage in vivo and in vitro.	Ginkgolides	32-43	AKT serine/threonine kinase 1	Rattus norvegicus	94-97	
29542683-10	2018	These observations suggest that ginkgolides act as novel extrinsic regulators activating both Akt/Nrf2 and Akt/CREB signaling pathways, protecting against cerebral ischemia/reperfusion (I/R) damage in vivo and in vitro.	Ginkgolides	32-43	AKT serine/threonine kinase 1	Rattus norvegicus	107-110	
35279613-0	2022	Extracts of Ginkgo flavonoids and ginkgolides improve cerebral ischaemia-reperfusion injury through the PI3K/Akt/Nrf2 signalling pathway and multicomponent in vivo processes.	Ginkgolides	34-45	AKT serine/threonine kinase 1	Rattus norvegicus	109-112	
35279613-13	2022	This result indicated that GF and GL might improve CIRI by activating the PI3K/Akt/Nrf2 signalling pathway and promoting multicomponent interactions in vivo.	Ginkgolides	34-36	AKT serine/threonine kinase 1	Rattus norvegicus	79-82	
33557607-0	2021	Ginkgolide B promotes oligodendrocyte precursor cell differentiation and survival via Akt/CREB/bcl-2 signaling pathway after white matter lesion.	Ginkgolides	0-10	AKT serine/threonine kinase 1	Rattus norvegicus	86-89	
32377729-0	2020	Ginkgolide B inhibits hydrogen peroxide-induced apoptosis and attenuates cytotoxicity via activating the PI3K/Akt/mTOR signaling pathway in H9c2 cells.	Ginkgolides	0-10	AKT serine/threonine kinase 1	Rattus norvegicus	110-113