PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17644565-4 2007 Treatment of A-10 VSMCs with S-nitroso-N-acetylpenicillamine (SNAP) or sodium nitroprusside (SNP), two NO donors, attenuated the ET-1-enhanced phosphorylation of several key components of growth-promoting and hypertrophic signaling pathways such as ERK1/2, PKB, and Pyk2. S-Nitroso-N-Acetylpenicillamine 29-60 endothelin 1 Homo sapiens 129-133 24697908-7 2014 ET-1 antagonized neural nitric oxide (NO)-mediated relaxant responses in LZR arteries, antagonizing relaxations induced by the NO donor S-nitroso-N-acetylpenicillamine to a larger extent in arteries from OZRs. S-Nitroso-N-Acetylpenicillamine 136-167 endothelin 1 Homo sapiens 0-4 17644565-4 2007 Treatment of A-10 VSMCs with S-nitroso-N-acetylpenicillamine (SNAP) or sodium nitroprusside (SNP), two NO donors, attenuated the ET-1-enhanced phosphorylation of several key components of growth-promoting and hypertrophic signaling pathways such as ERK1/2, PKB, and Pyk2. S-Nitroso-N-Acetylpenicillamine 62-66 endothelin 1 Homo sapiens 129-133 11738101-7 2001 Stimulation of HSCs with S-nitroso-N-acetyl-penicillamine (SNAP), a nitric oxide (NO)-donor, increased the opening of BK(Ca) channels and reduced the effects of endothelin-1. S-Nitroso-N-Acetylpenicillamine 25-57 endothelin 1 Homo sapiens 161-173 11738101-7 2001 Stimulation of HSCs with S-nitroso-N-acetyl-penicillamine (SNAP), a nitric oxide (NO)-donor, increased the opening of BK(Ca) channels and reduced the effects of endothelin-1. S-Nitroso-N-Acetylpenicillamine 59-63 endothelin 1 Homo sapiens 161-173 11078363-2 2000 Our aim was to compare the ability of the nitric oxide donors (NO-donors) 3-morpholinylsydnonimine (SIN-1) and S-nitroso-N-acetylpenicillamine (SNAP) with the novel nitric oxide donors (NONOates) diethylamine NONOate (DEA/NO), and diethylenetriamine NONOate (DETA/NO) in order to physiologically antagonize ET-1-mediated constriction of human internal mammary arteries (IMA) in vitro. S-Nitroso-N-Acetylpenicillamine 144-148 endothelin 1 Homo sapiens 307-311 8729059-5 1996 Higher concentrations of ET-1 (0.5 and 5 nM) produced a direct elevation in LVEDP which was enhanced by L-NAME and totally blocked by the NO donor S-nitrosoacetylpenicillamine (SNAP, 10 microM) although responses to 5 nM ET-1 were highly variable with no significant differences between treatment groups. S-Nitroso-N-Acetylpenicillamine 147-175 endothelin 1 Homo sapiens 25-29 8729059-5 1996 Higher concentrations of ET-1 (0.5 and 5 nM) produced a direct elevation in LVEDP which was enhanced by L-NAME and totally blocked by the NO donor S-nitrosoacetylpenicillamine (SNAP, 10 microM) although responses to 5 nM ET-1 were highly variable with no significant differences between treatment groups. S-Nitroso-N-Acetylpenicillamine 177-181 endothelin 1 Homo sapiens 25-29 8729059-5 1996 Higher concentrations of ET-1 (0.5 and 5 nM) produced a direct elevation in LVEDP which was enhanced by L-NAME and totally blocked by the NO donor S-nitrosoacetylpenicillamine (SNAP, 10 microM) although responses to 5 nM ET-1 were highly variable with no significant differences between treatment groups. S-Nitroso-N-Acetylpenicillamine 177-181 endothelin 1 Homo sapiens 221-225 10993771-5 2000 Sodium nitroprusside and S-nitroso-N-acetyl penicillamine significantly (P > 0.001) decreased ANG II and ET-1 secretion, whereas N(omega)-nitro-L-arginine-methyl ester enhanced it. S-Nitroso-N-Acetylpenicillamine 25-57 endothelin 1 Homo sapiens 108-112