PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26698536-0 2016 Pyridazinone derivatives displaying highly potent and selective inhibitory activities against c-Met tyrosine kinase. 2-phenyl-3(2H)-pyridazinone 0-12 met proto-oncogene Mus musculus 94-99 26698536-3 2016 A structure-activity relationship (SAR) study of these substances led to identification of pyridazinone 19 as a highly selective and potent c-Met tyrosine inhibitor, which displays favorable pharmacokinetic properties in mice and significant antitumor activity against a c-Met driven EBC-1 tumor xenograft. 2-phenyl-3(2H)-pyridazinone 91-103 met proto-oncogene Mus musculus 140-145 26698536-3 2016 A structure-activity relationship (SAR) study of these substances led to identification of pyridazinone 19 as a highly selective and potent c-Met tyrosine inhibitor, which displays favorable pharmacokinetic properties in mice and significant antitumor activity against a c-Met driven EBC-1 tumor xenograft. 2-phenyl-3(2H)-pyridazinone 91-103 met proto-oncogene Mus musculus 271-276