PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1310045-7	1992	Nearly identical binding to thrombin and elTM is observed when active-site-blocked activated bovine protein C is substituted for protein C. Thrombin inhibited by diisopropyl fluorophosphate and thrombin inhibited by a tripeptide chloromethyl ketone exhibited identical behavior in binding experiments, suggesting that the accessibility of protein C to the substrate recognition cleft of these two forms of thrombin is nearly equal.	Isoflurophate	162-189	coagulation factor II, thrombin	Bos taurus	28-36	
1310045-7	1992	Nearly identical binding to thrombin and elTM is observed when active-site-blocked activated bovine protein C is substituted for protein C. Thrombin inhibited by diisopropyl fluorophosphate and thrombin inhibited by a tripeptide chloromethyl ketone exhibited identical behavior in binding experiments, suggesting that the accessibility of protein C to the substrate recognition cleft of these two forms of thrombin is nearly equal.	Isoflurophate	162-189	coagulation factor II, thrombin	Bos taurus	140-148	
6725279-6	1984	Similar values for Ki were obtained when fibrinogen was used to inhibit the inactivation of bovine alpha- and beta-thrombin by diisopropylphosphorofluoridate.	Isoflurophate	127-157	coagulation factor II, thrombin	Bos taurus	115-123	
6896460-12	1982	The active site directed irreversible thrombin inhibitors diisopropyl phosphorofluoridate and D-phenylalanylprolylarginyl chloromethyl ketone displace DAPA from thrombin but not from prethrombin 2.	Isoflurophate	58-89	coagulation factor II, thrombin	Bos taurus	38-46	
6896460-12	1982	The active site directed irreversible thrombin inhibitors diisopropyl phosphorofluoridate and D-phenylalanylprolylarginyl chloromethyl ketone displace DAPA from thrombin but not from prethrombin 2.	Isoflurophate	58-89	coagulation factor II, thrombin	Bos taurus	161-169	
718867-8	1978	Displacement of factor Xa from the platelet receptor by diisopropyl fluorophosphate-factor Xa effectively blocked thrombin formation.	Isoflurophate	56-83	coagulation factor II, thrombin	Bos taurus	114-122	
11991818-2	2002	Bovine thrombin was treated with diisopropyl fluorophosphate, and prepared diisopropylphosphoryl-thrombin was used for the immunization to BALB/c mice.	Isoflurophate	33-60	coagulation factor II, thrombin	Bos taurus	7-15	
1964457-6	1990	The esterase activity was strongly inhibited by diisopropylfluorophosphate and phenylmethanesulfonyl fluoride, and to a lesser extent by tosyl-L-lysine chloromethyl ketone, indicating that the enzyme is a serine protease like thrombin.	Isoflurophate	48-74	coagulation factor II, thrombin	Bos taurus	226-234	
2501229-10	1989	Thrombin inactivated with diisopropylfluorophosphate (DFP) did not induce an increase in t-PA levels.	Isoflurophate	26-52	coagulation factor II, thrombin	Bos taurus	0-8	
2501229-10	1989	Thrombin inactivated with diisopropylfluorophosphate (DFP) did not induce an increase in t-PA levels.	Isoflurophate	54-57	coagulation factor II, thrombin	Bos taurus	0-8	
943183-2	1976	Upon incubation of the prothrombin for 30 h with a combination of neuraminidase, alpha- and beta-galactosidase and beta-N-acetylglucosaminidase in 4 mM diisopropylfluorophosphate at pH 5.3 and 30 degrees C, about 70% of the carbohydrates were removed without affecting the coagulation activity.	Isoflurophate	152-178	coagulation factor II, thrombin	Bos taurus	23-34