PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31885769-7 2019 Furthermore, L-cystathionine decreased the production of mitochondrial superoxide anion and the expression of Bax and restrained its translocation to mitochondria, increased mitochondrial membrane potential, inhibited mitochondrial permeability transition pore (MPTP) opening, suppressed the leakage of cytochrome c from mitochondria into the cytoplasm, and downregulated activities of caspase-9 and caspase-3. Cystathionine 13-28 caspase 3 Homo sapiens 400-409 31885769-8 2019 However, BTSA1, a Bax agonist, or Bax overexpression successfully abolished the inhibitory effect of L-cystathionine on Hcy-induced MPTP opening, caspase-9 and caspase-3 activation, and HUVEC apoptosis. Cystathionine 101-116 caspase 3 Homo sapiens 160-169