PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32986054-5 2020 In this study, we report on maghemite nanoparticles functionalized with citrate-, dextran- and polyethylene glycol coatings and their interaction with the clotting protein fibrinogen. Polyethylene Glycols 95-114 fibrinogen beta chain Homo sapiens 172-182 6978209-3 1981 It was shown that complex formation between fibrinogen and 125I-Clq occurs and that this complex precipitates in the presence of polyethylene glycol, leading to the false positive results in the ClqBA. Polyethylene Glycols 129-148 fibrinogen beta chain Homo sapiens 44-54 32986054-8 2020 In addition, bioconjugates of fibrinogen with dextran- and citrate-coated NPs interact with integrin-containing lipid bilayer, especially upon treatment with divalent ions, whereas PEG-coating reveals minor interaction. Polyethylene Glycols 181-184 fibrinogen beta chain Homo sapiens 30-40 24443272-6 2014 Our PEG-grafted channels showed significantly reduced fibrinogen adsorption and platelet adhesion up to 28 days after application, highlighting the stability and functionality of the coating over time. Polyethylene Glycols 4-7 fibrinogen beta chain Homo sapiens 54-64 29134801-7 2017 Although the optimized p(TMAEMA-b-MPC) and PLL-PEG copolymers were similarly fibrinogen-resistant, the cationic protein lysozyme was repelled by pMPC but adhered to the PEG brush via PEG-lysozyme attractions. Polyethylene Glycols 47-50 fibrinogen beta chain Homo sapiens 77-87 26966807-5 2016 Here we present results of explicit-solvent, all-atom MD simulations of the adsorption of the fibrinogen D-domain onto a graphene surface and a poly(ethylene glycol) (PEG) surface. Polyethylene Glycols 144-165 fibrinogen beta chain Homo sapiens 94-104 25542788-2 2015 Polyethylene glycol (PEG) hydrogels were formed with different protein constituents, including albumin, fibrinogen and gelatin. Polyethylene Glycols 0-19 fibrinogen beta chain Homo sapiens 104-114 25542788-2 2015 Polyethylene glycol (PEG) hydrogels were formed with different protein constituents, including albumin, fibrinogen and gelatin. Polyethylene Glycols 21-24 fibrinogen beta chain Homo sapiens 104-114 25542788-7 2015 Transverse MRI cross-sections of the implants revealed distinct mechanisms of the hydrogel"s biodegradation: PEG-Fibrinogen and PEG-Albumin underwent surface erosion, whereas PEG-Gelatin and PEG-DA hydrogels mainly underwent bulk degradation. Polyethylene Glycols 109-112 fibrinogen beta chain Homo sapiens 113-123 29022982-2 2017 We report here the influence of the poly(ethylene glycol) (PEG) grafting density in model phospholipid monolayers on the adsorption behavior of bovine serum albumin and human fibrinogen, not only with respect to the amount of adsorbed protein, but also its orientational ordering on the surface. Polyethylene Glycols 36-57 fibrinogen beta chain Homo sapiens 175-185 29022982-2 2017 We report here the influence of the poly(ethylene glycol) (PEG) grafting density in model phospholipid monolayers on the adsorption behavior of bovine serum albumin and human fibrinogen, not only with respect to the amount of adsorbed protein, but also its orientational ordering on the surface. Polyethylene Glycols 59-62 fibrinogen beta chain Homo sapiens 175-185 25462849-2 2015 A precursor solution of cells in photoreactive poly(ethylene glycol) (PEG)-fibrinogen (PF) polymer was transported through a transparent injector exposed to light irradiation before being atomized in a jet-in-air nozzle. Polyethylene Glycols 47-68 fibrinogen beta chain Homo sapiens 75-85 22820307-3 2012 To regulate the size and distance between patches of fibrinogen we developed a photolithography-based technique to fabricate patterns of proteins surrounded by a protein-repellant layer of poly(ethylene glycol). Polyethylene Glycols 189-210 fibrinogen beta chain Homo sapiens 53-63 32261321-3 2014 Compared to the pristine titanium, a highly hydrophilic layer was achieved after the immobilization, and the resulting heparin-PEG layer can significantly prevent human plasma fibrinogen adsorption. Polyethylene Glycols 127-130 fibrinogen beta chain Homo sapiens 176-186 24427541-7 2013 Images acquired with atomic force microscopy (AFM) disclose that fibrinogen attached primarily to the surface areas presenting thiol head groups, which were surrounded by PEG-silane. Polyethylene Glycols 171-174 fibrinogen beta chain Homo sapiens 65-75 22503950-7 2012 Results were compared to the non-fouling behavior of a PEGylated terpolymer formulation and it was observed that the poly(ethylene glycol)-containing materials were slightly more effective at resisting human umbilical vein endothelial cell adhesion and growth over a 7 day incubation period, but the zwitterion-containing materials were equally effective at resisting fibrinogen adsorption and platelet adhesion. Polyethylene Glycols 117-138 fibrinogen beta chain Homo sapiens 368-378 21440897-0 2011 Detection of nisin and fibrinogen adsorption on poly(ethylene oxide) coated polyurethane surfaces by time-of-flight secondary ion mass spectrometry (TOF-SIMS). Polyethylene Glycols 48-68 fibrinogen beta chain Homo sapiens 23-33 21435714-3 2011 We propose the use of polyethylene glycol (PEG)-based linkers that interact with fibrinogen via knob:hole affinity interactions as a means of controlling thrombin-mediated fibrin polymerization dynamics and resulting network structure. Polyethylene Glycols 22-41 fibrinogen beta chain Homo sapiens 81-91 21435714-3 2011 We propose the use of polyethylene glycol (PEG)-based linkers that interact with fibrinogen via knob:hole affinity interactions as a means of controlling thrombin-mediated fibrin polymerization dynamics and resulting network structure. Polyethylene Glycols 43-46 fibrinogen beta chain Homo sapiens 81-91 21435714-4 2011 Using bivalent and tetravalent knob-PEG conjugates with sizes ranging from 2 to 20 kDa, we demonstrate that the clotting characteristics of fibrinogen solutions can be altered in a dose-dependent manner, with conjugate size playing a major role in altering fibrin network structure. Polyethylene Glycols 36-39 fibrinogen beta chain Homo sapiens 140-150 21279672-7 2011 Meanwhile, the adsorption of blood proteins such as, human serum albumin (HSA) and fibrinogen was found considerably down-regulated in DLC-PEG-N-S, due mainly to the protein-repellent effect of PEG and zwitterion. Polyethylene Glycols 139-142 fibrinogen beta chain Homo sapiens 59-93 21391676-8 2011 Surprisingly, a monolayer of 5000 Da poly(ethylene glycol) (PEG5000) increased surface residence time and slowed diffusion of fibrinogen relative to bare fused silica or hydrophobically modified fused silica, suggesting that the mechanism of PEG resistance to protein adhesion is more sophisticated than the simple repulsion of individual proteins. Polyethylene Glycols 37-58 fibrinogen beta chain Homo sapiens 126-136 20594411-5 2011 The adsorption of vitronectin, thrombin, fibrinogen and complement component C3 was significantly lower on PEG hydrogels than on tissue culture polystyrene (TCPS). Polyethylene Glycols 107-110 fibrinogen beta chain Homo sapiens 41-51 20024308-1 2010 Selective chemical modification of a gold nano-cavity array is achieved via nanoscale templating to create fibrinogen patterned cavities with a polyethylene glycol modified top surface. Polyethylene Glycols 144-163 fibrinogen beta chain Homo sapiens 107-117 20801620-2 2010 In this work, the effects of the dextran and PEG on the morphology, wetting, and surface charge of the resulting surfaces were quantified and correlated with changes in the amount of fibrinogen and albumin adsorbed from aqueous solution. Polyethylene Glycols 45-48 fibrinogen beta chain Homo sapiens 183-193 20801620-8 2010 The PEG- and dextran-modified PDMS were exposed to BSA and fibrinogen to test their resistance to protein adsorption. Polyethylene Glycols 4-7 fibrinogen beta chain Homo sapiens 59-69 18342366-2 2008 To investigate this topic, a unique biomaterial system based on poly(ethylene glycol)-conjugated fibrinogen was adapted to study phenotypic plasticity in smooth muscle cells (SMCs) as a function of ECM mechanics in 3-D. Tuning the compressive modulus between 448 and 5804 Pa modestly regulated SMC cytoskeletal assembly in 3-D, with spread cells in stiff matrices having a slightly higher degree of F-actin bundling after prolonged culture. Polyethylene Glycols 64-85 fibrinogen beta chain Homo sapiens 97-107 18567052-0 2008 Interactions of KLVFF-PEG peptide conjugate with fibrinogen in neutral aqueous solutions. Polyethylene Glycols 22-25 fibrinogen beta chain Homo sapiens 49-59 18567052-2 2008 Our results show the formation of Fbg/KLVFF-PEG complexes for Delta > 0, such that there is not an extended network of complexes throughout the solution. Polyethylene Glycols 44-47 fibrinogen beta chain Homo sapiens 34-37 19693654-1 2010 Controllable bio-synthetic polymeric hydrogels made from fibrinogen-poly(ethylene glycol) adducts have been successfully employed in tissue engineering. Polyethylene Glycols 68-89 fibrinogen beta chain Homo sapiens 57-67 19693654-2 2010 The structural consequences of PEG conjugation to fibrinogen (i.e., PEGylation) in such a hydrogel network are not fully understood. Polyethylene Glycols 31-34 fibrinogen beta chain Homo sapiens 50-60 19693654-3 2010 The current investigation details the structural alterations caused to the reduced fibrinogen polypeptides by the covalent attachment of linear or branched PEG chains. Polyethylene Glycols 156-159 fibrinogen beta chain Homo sapiens 83-93 19798675-7 2009 The soluble fraction of the PEG 2-4% precipitate (PS4%), analyzed by non-denaturing 2-DE and MALDI-MS PMF, contained C4b-binding protein and its complex with complement C4, low-density lipoproteins, IgM, and complement C1 subcomponent q, together with Fb, FN, and their oligomers. Polyethylene Glycols 28-31 fibrinogen beta chain Homo sapiens 252-254 17597372-1 2008 The present work focus on the adsorption of fibrinogen (Fgn) on to the semi-interpenetrating polymer networks (IPNs) of polyethylene glycol (PEG) and poly(2-hydroxyethyl methacrylate-co-acrylonitrile) and attempts to correlate the adsorption behaviour of proteins to the blood compatible aspects of the polymeric surfaces. Polyethylene Glycols 120-139 fibrinogen beta chain Homo sapiens 44-54 17920250-5 2008 However, fibrinogen and albumin adsorption significantly increased on all surfaces after PEG or MPEG backfilling. Polyethylene Glycols 89-92 fibrinogen beta chain Homo sapiens 9-19 17597372-1 2008 The present work focus on the adsorption of fibrinogen (Fgn) on to the semi-interpenetrating polymer networks (IPNs) of polyethylene glycol (PEG) and poly(2-hydroxyethyl methacrylate-co-acrylonitrile) and attempts to correlate the adsorption behaviour of proteins to the blood compatible aspects of the polymeric surfaces. Polyethylene Glycols 120-139 fibrinogen beta chain Homo sapiens 56-59 17597372-1 2008 The present work focus on the adsorption of fibrinogen (Fgn) on to the semi-interpenetrating polymer networks (IPNs) of polyethylene glycol (PEG) and poly(2-hydroxyethyl methacrylate-co-acrylonitrile) and attempts to correlate the adsorption behaviour of proteins to the blood compatible aspects of the polymeric surfaces. Polyethylene Glycols 141-144 fibrinogen beta chain Homo sapiens 44-54 17597372-1 2008 The present work focus on the adsorption of fibrinogen (Fgn) on to the semi-interpenetrating polymer networks (IPNs) of polyethylene glycol (PEG) and poly(2-hydroxyethyl methacrylate-co-acrylonitrile) and attempts to correlate the adsorption behaviour of proteins to the blood compatible aspects of the polymeric surfaces. Polyethylene Glycols 141-144 fibrinogen beta chain Homo sapiens 56-59 16457880-9 2006 Relative differences in platelet adhesion on PEG-NHS and PEG-DISO modified surfaces could be attributed to differences in reactivity towards fibrinogen and the size of the polymer backbone. Polyethylene Glycols 45-48 fibrinogen beta chain Homo sapiens 141-151 17291015-7 2007 While we did not find an overall correlation between surface air-water contact angle measurements and fibrinogen adsorption (R2 = 0.08), our data demonstrate that gradually increasing the poly(ethylene glycol) content within a subgroup of polymers having the same polymer backbone will lead to decreased fibrinogen adsorption. Polyethylene Glycols 188-209 fibrinogen beta chain Homo sapiens 304-314 17723439-2 2006 In the pH 6.2 buffer solution and in the presence of polyethylene glycol (PEG), the immune reaction between gold-labeled goat anti-human fibrinogen and fibrinogen took place and the labeled gold nanoparticles were released from the goat anti-human fibrinogen, and the released gold particles aggregated which leaded the resonance scattering intensity at 560 nm (I560 nm) to enhance greatly. Polyethylene Glycols 53-72 fibrinogen beta chain Homo sapiens 137-147 17723439-2 2006 In the pH 6.2 buffer solution and in the presence of polyethylene glycol (PEG), the immune reaction between gold-labeled goat anti-human fibrinogen and fibrinogen took place and the labeled gold nanoparticles were released from the goat anti-human fibrinogen, and the released gold particles aggregated which leaded the resonance scattering intensity at 560 nm (I560 nm) to enhance greatly. Polyethylene Glycols 53-72 fibrinogen beta chain Homo sapiens 152-162 17723439-2 2006 In the pH 6.2 buffer solution and in the presence of polyethylene glycol (PEG), the immune reaction between gold-labeled goat anti-human fibrinogen and fibrinogen took place and the labeled gold nanoparticles were released from the goat anti-human fibrinogen, and the released gold particles aggregated which leaded the resonance scattering intensity at 560 nm (I560 nm) to enhance greatly. Polyethylene Glycols 53-72 fibrinogen beta chain Homo sapiens 152-162 17723439-2 2006 In the pH 6.2 buffer solution and in the presence of polyethylene glycol (PEG), the immune reaction between gold-labeled goat anti-human fibrinogen and fibrinogen took place and the labeled gold nanoparticles were released from the goat anti-human fibrinogen, and the released gold particles aggregated which leaded the resonance scattering intensity at 560 nm (I560 nm) to enhance greatly. Polyethylene Glycols 74-77 fibrinogen beta chain Homo sapiens 137-147 17723439-2 2006 In the pH 6.2 buffer solution and in the presence of polyethylene glycol (PEG), the immune reaction between gold-labeled goat anti-human fibrinogen and fibrinogen took place and the labeled gold nanoparticles were released from the goat anti-human fibrinogen, and the released gold particles aggregated which leaded the resonance scattering intensity at 560 nm (I560 nm) to enhance greatly. Polyethylene Glycols 74-77 fibrinogen beta chain Homo sapiens 152-162 17723439-2 2006 In the pH 6.2 buffer solution and in the presence of polyethylene glycol (PEG), the immune reaction between gold-labeled goat anti-human fibrinogen and fibrinogen took place and the labeled gold nanoparticles were released from the goat anti-human fibrinogen, and the released gold particles aggregated which leaded the resonance scattering intensity at 560 nm (I560 nm) to enhance greatly. Polyethylene Glycols 74-77 fibrinogen beta chain Homo sapiens 152-162 16457880-9 2006 Relative differences in platelet adhesion on PEG-NHS and PEG-DISO modified surfaces could be attributed to differences in reactivity towards fibrinogen and the size of the polymer backbone. Polyethylene Glycols 57-60 fibrinogen beta chain Homo sapiens 141-151 16555112-1 2006 The influence of different surface modifications with poly(ethyleneglycol) (PEG) layers on the adsorption of fibrinogen and the adhesion and activation of macrophage-like human leukocytes was investigated. Polyethylene Glycols 54-74 fibrinogen beta chain Homo sapiens 109-119 16243393-7 2006 Increased concentrations of the synthetic PEG are used to further alter the network structure of the PEG-fibrinogen hydrogel. Polyethylene Glycols 42-45 fibrinogen beta chain Homo sapiens 105-115 16555112-6 2006 The results showed that PEGylated surfaces adsorbed significantly less (up to 90% less) fibrinogen, and that unfolding of adsorbed fibrinogen was more pronounced on the linear mPEG layers than on the PEG-like plasma polymer surfaces. Polyethylene Glycols 24-27 fibrinogen beta chain Homo sapiens 88-98 16555112-1 2006 The influence of different surface modifications with poly(ethyleneglycol) (PEG) layers on the adsorption of fibrinogen and the adhesion and activation of macrophage-like human leukocytes was investigated. Polyethylene Glycols 76-79 fibrinogen beta chain Homo sapiens 109-119 16378437-6 2006 The plasma polymer coatings with the greatest protein-repelling properties were the most PEG-like in nature and showed the strongest repulsion in interaction force measurements with the fibrinogen-coated probe. Polyethylene Glycols 89-92 fibrinogen beta chain Homo sapiens 186-196 7482443-1 1995 Polyethylene glycol(PEG) was used to precipitate fibrinogen to prepare defibrinated plasma in the two stage clotting assay of antithrombin activity. Polyethylene Glycols 0-19 fibrinogen beta chain Homo sapiens 49-59 16499438-5 2006 We have developed a PEGylated fibrin patch for MSC transplantation by modifying fibrinogen (Fgn) with the benzotriazole carbonate derivative of PEG to create secondary crosslinking. Polyethylene Glycols 20-23 fibrinogen beta chain Homo sapiens 80-90 16499438-5 2006 We have developed a PEGylated fibrin patch for MSC transplantation by modifying fibrinogen (Fgn) with the benzotriazole carbonate derivative of PEG to create secondary crosslinking. Polyethylene Glycols 20-23 fibrinogen beta chain Homo sapiens 92-95 15853141-6 2005 Furthermore, all the PEG films were evaluated for their ability to control biofouling using albumin and fibrinogen as the model proteins. Polyethylene Glycols 21-24 fibrinogen beta chain Homo sapiens 104-114 10403044-1 1999 The in vitro protein-rejecting properties of PEG-coated polyalkylcyanoacrylate (PACA) nanoparticles were for the first time visualized after freeze-fracture of the nanoparticles pre-incubated with fibrinogen as a model blood protein. Polyethylene Glycols 45-48 fibrinogen beta chain Homo sapiens 197-207 11400130-0 2001 Modification of fibrinogen with poly(ethylene glycol) and its effects on fibrin clot characteristics. Polyethylene Glycols 32-52 fibrinogen beta chain Homo sapiens 16-26 11400130-2 2001 Poly(ethylene glycol) (PEG) offers potential solutions to these problems by providing a mechanism for increasing the number of crosslinks between adjacent fibrin monomer molecules or for covalently crosslinking Fgn to therapeutic agents. Polyethylene Glycols 0-21 fibrinogen beta chain Homo sapiens 211-214 11400130-2 2001 Poly(ethylene glycol) (PEG) offers potential solutions to these problems by providing a mechanism for increasing the number of crosslinks between adjacent fibrin monomer molecules or for covalently crosslinking Fgn to therapeutic agents. Polyethylene Glycols 23-26 fibrinogen beta chain Homo sapiens 211-214 11400130-4 2001 This study characterizes the clot characteristics of Fgn modified to varying degrees with monofunctional succinimidyl propionate PEG (5000 Da). Polyethylene Glycols 129-132 fibrinogen beta chain Homo sapiens 53-56 11400130-5 2001 The data indicate that, although thrombin clotting times are significantly altered, Fgn maintains 90% of its capacity to clot upon the addition of up to 5 PEG/Fgn. Polyethylene Glycols 155-158 fibrinogen beta chain Homo sapiens 84-87 9616708-0 1997 Fibrinogen-dependent adherence of macrophages to surfaces coated with poly(ethylene oxide)/poly(propylene oxide) triblock copolymers. Polyethylene Glycols 70-90 fibrinogen beta chain Homo sapiens 0-10 8788102-2 1996 Adsorbed fibrinogen at steady state decreased in the order PU-SO3 > PU > PU-PEO-SO3 > PU-PEO, suggesting that sulfonate groups have specific high affinity to fibrinogen. Polyethylene Glycols 82-85 fibrinogen beta chain Homo sapiens 9-19 8788102-4 1996 In addition, PU-PEO-SO3 showed a very fast fibrinogen adsorption due to the high accessibility of the sulfonate group to fibrinogen by the poly(ethylene oxide) (PEO) spacer. Polyethylene Glycols 139-159 fibrinogen beta chain Homo sapiens 43-53 8788102-4 1996 In addition, PU-PEO-SO3 showed a very fast fibrinogen adsorption due to the high accessibility of the sulfonate group to fibrinogen by the poly(ethylene oxide) (PEO) spacer. Polyethylene Glycols 139-159 fibrinogen beta chain Homo sapiens 121-131 7482443-1 1995 Polyethylene glycol(PEG) was used to precipitate fibrinogen to prepare defibrinated plasma in the two stage clotting assay of antithrombin activity. Polyethylene Glycols 20-23 fibrinogen beta chain Homo sapiens 49-59 25147429-9 1994 The influence of the surface density of the grafted PEG chains on protein repellence was tested by the adsorption of fibrinogen from solution and from a ternary protein solution mixture containing fibrinogen, albumin and immunoglobulin G. Fibrinogen adsorption onto the silica end of the gradient was extremely low, both in the presence of the other two proteins and in their absence. Polyethylene Glycols 52-55 fibrinogen beta chain Homo sapiens 117-127 7738068-2 1995 Increasing the molecular weight of PEG in the matrix from 1000 to 100,000 g/mol reduced the advancing and receding contact angles, contact angle hysteresis, and adsorption of human fibrinogen and bovine serum albumin. Polyethylene Glycols 35-38 fibrinogen beta chain Homo sapiens 181-191 25147429-10 1994 As the surface density of the grafted PEG chains increased, so did the fibrinogen adsorption (up to 0.024 mug cm-2). Polyethylene Glycols 38-41 fibrinogen beta chain Homo sapiens 71-81 8031988-7 1994 Adsorption of fibrinogen, in particular, was significantly reduced by the amphiphilic additives to levels similar to those obtained for Pellethane surfaces grafted with PEG 20,000. Polyethylene Glycols 169-172 fibrinogen beta chain Homo sapiens 14-24 8266923-6 1993 In HIV-seronegative ITP patients, the decrease or disappearance of anti-platelet antibodies directly correlated with the decreased inhibition of GPIIb/IIIa binding to fibrinogen by the 2% PEG supernatants of sera which contained anti-platelet antibodies. Polyethylene Glycols 188-191 fibrinogen beta chain Homo sapiens 167-177 8241058-0 1993 Adsorption behavior of fibrinogen to sulfonated polyethyleneoxide-grafted polyurethane surfaces. Polyethylene Glycols 48-65 fibrinogen beta chain Homo sapiens 23-33 1858340-1 1991 Simple procedure was developed for production of fibrinogen concentrate from small amounts of human autogenous blood using precipitation with polyethylene glycol and ammonium sulfate. Polyethylene Glycols 142-161 fibrinogen beta chain Homo sapiens 49-59 1385983-6 1992 Plasma fibrinogen was observed to play an important role in the adhesion of all three of these species on both the polyethylene oxide-modified and control polyethylene terephthalate materials. Polyethylene Glycols 115-133 fibrinogen beta chain Homo sapiens 7-17 1420713-9 1992 The presence of 19 ethylene oxide residues in the hydrophilic poly(ethylene oxide) chains was sufficient to repel fibrinogen and platelets by the mechanism of steric repulsion. Polyethylene Glycols 62-82 fibrinogen beta chain Homo sapiens 114-124 1429764-1 1992 Whereas it has been commonly thought that adding polyethylene oxide PEO to a surface would diminish the capacity of the surface to cause deposition of platelets and of fibrinogen, and to activate complement C3, we present data showing exactly the opposite. Polyethylene Glycols 49-67 fibrinogen beta chain Homo sapiens 168-178 1527100-0 1992 Reduction of fibrinogen adsorption on PEG-coated polystyrene surfaces. Polyethylene Glycols 38-41 fibrinogen beta chain Homo sapiens 13-23 1527100-5 1992 The results of protein adsorption studies showed that fibrinogen adsorption is significantly reduced by coating polystyrene with either linear or branched PEGs of 1500 to 20,000 in molecular weight. Polyethylene Glycols 155-159 fibrinogen beta chain Homo sapiens 54-64 1858340-2 1991 Maximal yield of fibrinogen was obtained using polyethylene glycol 2,000 and 6,000 daltons at concentrations 7% and 4.5%, respectively. Polyethylene Glycols 47-66 fibrinogen beta chain Homo sapiens 17-27 2443781-2 1987 Autologous fibrinogen, derived by polyethylene glycol precipitation from the blood of an individual patient would avoid this risk, and has been shown to be relatively safe to the ear in animal studies. Polyethylene Glycols 34-53 fibrinogen beta chain Homo sapiens 11-21 2475731-7 1989 In addition to the commercial products, the self-made fibrinogen glues, especially the PEG glue, were also strong enough for otolaryngological use. Polyethylene Glycols 87-90 fibrinogen beta chain Homo sapiens 54-64 2443781-5 1987 When 10% polyethylene glycol was used to precipitate the fibrinogen, the concentrate contained, on the average, 31.8 mg of fibrinogen/ml. Polyethylene Glycols 9-28 fibrinogen beta chain Homo sapiens 57-67 2443781-5 1987 When 10% polyethylene glycol was used to precipitate the fibrinogen, the concentrate contained, on the average, 31.8 mg of fibrinogen/ml. Polyethylene Glycols 9-28 fibrinogen beta chain Homo sapiens 123-133 2443781-7 1987 Increasing the polyethylene glycol concentration in the precipitation process to as high as 15% resulted in an increased yield as high as 91%, but the protein in the final product was only 42.5% fibrinogen. Polyethylene Glycols 15-34 fibrinogen beta chain Homo sapiens 195-205 2443781-8 1987 Polyacrylamide gel electrophoresis confirmed that the predominant protein in the 10% polyethylene glycol precipitate was fibrinogen. Polyethylene Glycols 85-104 fibrinogen beta chain Homo sapiens 121-131 6868007-1 1983 Fibrinogen was isolated from human plasma using a polyethylene glycol 1000 fractionation procedure that eliminates problems of denaturation, degradation and contamination encountered with other procedures (1). Polyethylene Glycols 50-69 fibrinogen beta chain Homo sapiens 0-10 2418738-4 1986 The fibrinogen and factor XIII component of the adhesive was isolated by polyethylene glycol precipitation from human plasma within a few hours, and was used either immediately or frozen for use up to 3 weeks later. Polyethylene Glycols 73-92 fibrinogen beta chain Homo sapiens 4-14