PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34558577-6 2021 Meanwhile, CGA caused strong inhibition against the increase of liver injury markers (i.e. AST, ALT and ALP), hepatic inflammatory cytokines (i.e. IL-1, IL-6, TNF-alpha and TNF-beta) and dyslipidemia (i.e. TC, TG, LDL-C and HDL-C) in L-carnitine-fed mice (p < 0.05). Carnitine 234-245 interleukin 6 Mus musculus 153-157 26647854-10 2016 GW9662 also eliminated the inhibitory effect of L-carnitine on the expression of cyclooxygenase-2 (Cox-2) in the liver, and on the serum expression levels of pro-inflammatory prostaglandin E2, C-reactive protein, tumor necrosis factor-alpha and interleukin-6 in the cancer cachexia model mice. Carnitine 48-59 interleukin 6 Mus musculus 245-258 26452216-10 2015 The elevated serum concentrations of interleukin (IL)-6 and tumor necrosis factor-alpha (TNF-alpha) were decreased by L-carnitine. Carnitine 118-129 interleukin 6 Mus musculus 37-55 23970467-7 2013 Relative to vehicle, L-carnitine treatment of mouse dry eye for 14 days (days 21 to 35) resulted in a significant reduction in corneal staining, number of TUNEL-positive cells, and expression of TNF-alpha, IL-17, IL-6, or IL-1beta, as well as significantly increased the number of goblet cells. Carnitine 21-32 interleukin 6 Mus musculus 213-217 21532335-8 2011 These effects of L-carnitine on cancer cachexia mice were accompanied by the upregulation of mRNA level of CPT I and II and increased enzyme activity of CPT I in the liver, as well as the downregulation of serum TNF-alpha and IL-6 levels. Carnitine 17-28 interleukin 6 Mus musculus 226-230 21532335-9 2011 Moreover, free carnitine levels were negatively correlated with serum TNF-alpha or IL-6 level. Carnitine 15-24 interleukin 6 Mus musculus 83-87 15811520-3 2005 The present study has examined whether administration of L-carnitine to young female mice alters the percentage of immune cells in peritoneal exudates and the uterus as well as the levels of IFN-gamma, TNF-alpha, IL-2, IL-4, IL-6, VEGF, GM-CSF and IGF-I in blood serum, peritoneal fluid and supernatants of uterine cultured cells as tested by immunofluorescence or ELISA techniques, respectively, leading to a pathological disorder resembling human endometriosis. Carnitine 57-68 interleukin 6 Mus musculus 225-229 31039949-11 2019 In the PCOS+l-carnitine group, serum concentrations of FSH and FRAP increased significantly, whereas there were significant decreases in serum concentrations of testosterone, LH, MDA, IL-6 and TNF-alpha, as well as in the percentage of TUNEL-positive apoptotic cells, compared with the PCOS group. Carnitine 12-23 interleukin 6 Mus musculus 184-188 34724970-15 2021 Moreover, L-carnitine reduced the serum levels of IL-1 and IL-6, factors known to induce cancer cachexia. Carnitine 10-21 interleukin 6 Mus musculus 59-63 35500571-10 2022 In the autografted+l-carnitine group, serum concentrations of IL-6, TNF-alpha and MDA were significantly decreased compared to the autografted group. Carnitine 19-30 interleukin 6 Mus musculus 62-66 32342686-3 2020 High intake of L-carnitine also induced liver injury, which was proved by the increases in the serum AST and ALT activities, production of inflammatory liver cytokines (IL-1, IL-6, TNF-alpha and TNF-beta), lipid metabolism (TC, TG, HDL and LDL) disorder, and the decline in antioxidant ability (SOD, GSH-Px, MDA and RAHFR). Carnitine 15-26 interleukin 6 Mus musculus 175-179