PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26647854-10	2016	GW9662 also eliminated the inhibitory effect of L-carnitine on the expression of cyclooxygenase-2 (Cox-2) in the liver, and on the serum expression levels of pro-inflammatory prostaglandin E2, C-reactive protein, tumor necrosis factor-alpha and interleukin-6 in the cancer cachexia model mice.	Carnitine	48-59	interleukin 6	Mus musculus	245-258	
21532335-8	2011	These effects of L-carnitine on cancer cachexia mice were accompanied by the upregulation of mRNA level of CPT I and II and increased enzyme activity of CPT I in the liver, as well as the downregulation of serum TNF-alpha and IL-6 levels.	Carnitine	17-28	interleukin 6	Mus musculus	226-230	
23970467-7	2013	Relative to vehicle, L-carnitine treatment of mouse dry eye for 14 days (days 21 to 35) resulted in a significant reduction in corneal staining, number of TUNEL-positive cells, and expression of TNF-alpha, IL-17, IL-6, or IL-1beta, as well as significantly increased the number of goblet cells.	Carnitine	21-32	interleukin 6	Mus musculus	213-217	
26452216-10	2015	The elevated serum concentrations of interleukin (IL)-6 and tumor necrosis factor-alpha (TNF-alpha) were decreased by L-carnitine.	Carnitine	118-129	interleukin 6	Mus musculus	37-55	
21532335-9	2011	Moreover, free carnitine levels were negatively correlated with serum TNF-alpha or IL-6 level.	Carnitine	15-24	interleukin 6	Mus musculus	83-87	
15811520-3	2005	The present study has examined whether administration of L-carnitine to young female mice alters the percentage of immune cells in peritoneal exudates and the uterus as well as the levels of IFN-gamma, TNF-alpha, IL-2, IL-4, IL-6, VEGF, GM-CSF and IGF-I in blood serum, peritoneal fluid and supernatants of uterine cultured cells as tested by immunofluorescence or ELISA techniques, respectively, leading to a pathological disorder resembling human endometriosis.	Carnitine	57-68	interleukin 6	Mus musculus	225-229	
34558577-6	2021	Meanwhile, CGA caused strong inhibition against the increase of liver injury markers (i.e. AST, ALT and ALP), hepatic inflammatory cytokines (i.e. IL-1, IL-6, TNF-alpha and TNF-beta) and dyslipidemia (i.e. TC, TG, LDL-C and HDL-C) in L-carnitine-fed mice (p < 0.05).	Carnitine	234-245	interleukin 6	Mus musculus	153-157	
34724970-15	2021	Moreover, L-carnitine reduced the serum levels of IL-1 and IL-6, factors known to induce cancer cachexia.	Carnitine	10-21	interleukin 6	Mus musculus	59-63	
32342686-3	2020	High intake of L-carnitine also induced liver injury, which was proved by the increases in the serum AST and ALT activities, production of inflammatory liver cytokines (IL-1, IL-6, TNF-alpha and TNF-beta), lipid metabolism (TC, TG, HDL and LDL) disorder, and the decline in antioxidant ability (SOD, GSH-Px, MDA and RAHFR).	Carnitine	15-26	interleukin 6	Mus musculus	175-179	
31039949-11	2019	In the PCOS+l-carnitine group, serum concentrations of FSH and FRAP increased significantly, whereas there were significant decreases in serum concentrations of testosterone, LH, MDA, IL-6 and TNF-alpha, as well as in the percentage of TUNEL-positive apoptotic cells, compared with the PCOS group.	Carnitine	12-23	interleukin 6	Mus musculus	184-188	
35500571-10	2022	In the autografted+l-carnitine group, serum concentrations of IL-6, TNF-alpha and MDA were significantly decreased compared to the autografted group.	Carnitine	19-30	interleukin 6	Mus musculus	62-66