PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23771822-6 2013 OCTN3, identified only in mouse, mediates also carnitine transport. Carnitine 47-56 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 0-5 22952014-9 2013 Rodent Octn3 transports carnitine specifically, particularly in male reproductive tissues. Carnitine 24-33 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 7-12 16051193-2 2005 The gene products octn2 and octn3, which transport carnitine with high affinity, are both expressed in testis, where carnitine is required to maintain sperm cell motility. Carnitine 51-60 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 28-33 18296741-8 2008 In conclusion, this study shows that transcriptional upregulation of OCTN2 and OCTN3 in tissues and of enzymes involved in hepatic carnitine biosynthesis are mediated by PPAR alpha. Carnitine 131-140 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 79-84 17965255-0 2007 Transport of carnitine and acetylcarnitine by carnitine/organic cation transporter (OCTN) 2 and OCTN3 into epididymal spermatozoa. Carnitine 13-22 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 96-101 17965255-7 2007 We conclude that both Na(+)-dependent and -independent carnitine transporters, OCTN2 and OCTN3, mediate the supply of carnitine and acetylcarnitine to epididymal spermatozoa in mice. Carnitine 55-64 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 89-94 16051193-2 2005 The gene products octn2 and octn3, which transport carnitine with high affinity, are both expressed in testis, where carnitine is required to maintain sperm cell motility. Carnitine 117-126 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 28-33 16051193-9 2005 Furthermore, the expressions of both of octn2 and octn3 genes in TM4 cells were up-regulated by palmitic acid, whereas carnitine increased only the expression of octn2 without any change in octn3 expression. Carnitine 119-128 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 190-195 16051193-10 2005 Accordingly, the expressions of octn2 and 3 are regulated by distinct mechanisms, suggesting distinct roles of octn2 and octn3 in carnitine transport. Carnitine 130-139 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 121-126 11010964-8 2000 The relative uptake activity ratios of carnitine to TEA were 1.78, 11.3, and 746 for OCTN1, -2, and -3, respectively, suggesting high specificity of OCTN3 for carnitine and significantly lower carnitine transport activity of OCTN1. Carnitine 39-48 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 149-154 11010964-8 2000 The relative uptake activity ratios of carnitine to TEA were 1.78, 11.3, and 746 for OCTN1, -2, and -3, respectively, suggesting high specificity of OCTN3 for carnitine and significantly lower carnitine transport activity of OCTN1. Carnitine 159-168 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 149-154 11010964-8 2000 The relative uptake activity ratios of carnitine to TEA were 1.78, 11.3, and 746 for OCTN1, -2, and -3, respectively, suggesting high specificity of OCTN3 for carnitine and significantly lower carnitine transport activity of OCTN1. Carnitine 159-168 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 149-154 11010964-9 2000 Thus, OCTN3 is unique in its limited tissue distribution and Na(+)-independent carnitine transport, whereas OCTN1 efficiently transported TEA with minimal expression of carnitine transport activity and may have a different role from other members of the OCTN family. Carnitine 79-88 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 6-11 12889657-7 2003 A third organic/cation carnitine transporter with high specificity for carnitine, Octn3, has been cloned in mice. Carnitine 23-32 solute carrier family 22 (organic cation transporter), member 21 Mus musculus 82-87