PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20093144-7 2010 Furthermore, mitochondrial dysfunction associated with cell apoptosis including membrane potential loss, down-regulation of Bcl-2 and up-regulation of Bax and the release of cytochrome c were abrogated in the presence of L-carnitine. Carnitine 221-232 BCL2 associated X, apoptosis regulator Homo sapiens 151-154 19619983-10 2009 At the molecular level, the expression of proapoptotic Bax and Bak proteins were increased in cells incubated with butyrate and carnitine, whereas expression of antiapoptotic Bcl-x(L) was decreased. Carnitine 128-137 BCL2 associated X, apoptosis regulator Homo sapiens 55-58 25220073-5 2014 L-carnitine suppress the endoplasmic reticulum dilation and activation of ER stress-associated proteins including glucose-regulated protein 78 (GRP78), CCAAT/enhancer-binding protein-homologous protein (CHOP), JNK, Bax and Bim induced by H2O2 or TM. Carnitine 0-11 BCL2 associated X, apoptosis regulator Homo sapiens 215-218 35304586-7 2022 Therefore, by reducing the level of IRE1alpha, L-Carnitine reduced the levels of Beclin and LC3BII, consequently reducing the level of apoptotic biomarkers including Bax and cleaving PARP and caspase 3. Carnitine 47-58 BCL2 associated X, apoptosis regulator Homo sapiens 166-169 27569824-13 2016 CONCLUSION: L-carnitine may reduce cardiopulmonary bypass-induced myocardial apoptosis through modulating the expressions of Bcl-2 and Bax, resulting in a protective effect from MIRI. Carnitine 12-23 BCL2 associated X, apoptosis regulator Homo sapiens 135-138 21756550-7 2011 Meanwhile, H(2)O(2)-induced down-regulation of Bcl-2, up-regulation of Bax, and DNA damage and apoptosis were also inhibited in the presence of L-carnitine. Carnitine 144-155 BCL2 associated X, apoptosis regulator Homo sapiens 71-74 25247444-9 2014 Cell apoptosis triggered by high glucose was also inhibited by L-carnitine, characterized by the downregulation of caspase-9, caspase-3 and Bax/Bcl-2. Carnitine 63-74 BCL2 associated X, apoptosis regulator Homo sapiens 140-143