PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35176959-0 2022 L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and CASP-3 signaling. Carnitine 0-11 caspase 3 Rattus norvegicus 162-168 34979196-12 2022 Caspase-3 expression in hepatocytes was decreased in Pb-treated group supplemented with l-carnitine. Carnitine 88-99 caspase 3 Rattus norvegicus 0-9 35176959-11 2022 It can be concluded that LC alleviates LTZ induced hepatorenal oxidative stress (OS) and mitochondrial-dependent apoptotic progression through modulation of Nrf-2, Cyt c, and CASP-3 signaling in female rats. Carnitine 25-27 caspase 3 Rattus norvegicus 175-181 29538301-11 2018 Moreover, l-Car significantly reduced PTZ-induced elevation in protein expression of caspase-3 (p < 0.0001) and beta-catenin (p < 0.0001). Carnitine 10-15 caspase 3 Rattus norvegicus 85-94 33613972-6 2021 LCAR significantly declined serum urea and creatinine concentrations, restored oxidant/antioxidant balance, reversed inflammation, and antagonized caspase 3-mediated apoptotic cell death in renal tissues. Carnitine 0-4 caspase 3 Rattus norvegicus 147-156 29499191-7 2018 L-carnitine significantly attenuated UVA-induced elevation of the DNA damage markers 8-oxo-2"-deoxyguanosine (8-oxo-dG) and cyclobutane pyrimidine dimers (CPDs) as well as decreased DNA fragmentation and the activity of the apoptotic marker caspase-3. Carnitine 0-11 caspase 3 Rattus norvegicus 241-250 24157049-9 2013 Furthermore, the administration of L-carnitine at a high dose inhibited the expression of caspase-3 and LC3-II. Carnitine 35-46 caspase 3 Rattus norvegicus 90-99 26888052-8 2016 Pretreatment with L-carnitine particularly at high-dose reduced toxicity and prevented the hepatocytes from abnormal caspase-3 activity and apoptosis. Carnitine 18-29 caspase 3 Rattus norvegicus 117-126 22608917-6 2012 Interestingly, L-carnitine treatment also decreases caspase-3 mRNA content therefore suggesting a modulation of apoptosis. Carnitine 15-26 caspase 3 Rattus norvegicus 52-61