PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9507015-6	1998	Plating cells on poly-L-lysine prevented focal adhesion formation, eliminated IL-1-induced calcium influx, abolished ERK stimulation, and blocked c-fos expression.	Lysine	17-30	interleukin 1 alpha	Homo sapiens	78-82	
19112497-7	2008	Furthermore, lysine-deficient TRAF6 rescued IL-1-mediated NFkappaB and MAPK activation, as well as IL-6 elaboration in retrovirally-rescued TRAF6-deficient fibroblasts.	Lysine	13-19	interleukin 1 alpha	Homo sapiens	44-48	
17449468-5	2007	The NZF domains of TAB2/3 are critical for TAB2/3 to bind to Lys(63)-linked polyubiquitin chains of other adaptor proteins, such as receptor-interacting protein and TRAF6, which are two signaling proteins essential for TNF- and IL-1-induced NF-kappaB activation, respectively.	Lysine	61-64	interleukin 1 alpha	Homo sapiens	228-232	
16996234-0	2006	Determination of interleukin-1alpha in human NCTC 2544 keratinocyte cells as a predictor of skin irritation from lysine-based surfactants.	Lysine	113-119	interleukin 1 alpha	Homo sapiens	17-35	
16996234-5	2006	Lysine derivatives proved to be less potent in stimulating IL-1 alpha synthesis and induced a lower release of this cytokine into the culture medium when compared to the anionic surfactant sodium dodecyl sulfate.	Lysine	0-6	interleukin 1 alpha	Homo sapiens	59-69	
9507015-10	1998	The focal adhesion dependence of IL-1-induced ERK activation and c-fos expression could be circumvented in cells plated on poly-L-lysine by simultaneous incubation with IL-1 and the calcium ionophore ionomycin.	Lysine	123-136	interleukin 1 alpha	Homo sapiens	33-37	
9507015-10	1998	The focal adhesion dependence of IL-1-induced ERK activation and c-fos expression could be circumvented in cells plated on poly-L-lysine by simultaneous incubation with IL-1 and the calcium ionophore ionomycin.	Lysine	123-136	interleukin 1 alpha	Homo sapiens	169-173	
20074553-4	2010	In addition, the degradation of non-ubiquitinated form of lysine less mutant p21-K6R was also inhibited by IL-1, suggesting that IL-1 stabilized p21 protein via ubiquitin-independent pathway.	Lysine	58-64	interleukin 1 alpha	Homo sapiens	107-111	
20074553-4	2010	In addition, the degradation of non-ubiquitinated form of lysine less mutant p21-K6R was also inhibited by IL-1, suggesting that IL-1 stabilized p21 protein via ubiquitin-independent pathway.	Lysine	58-64	interleukin 1 alpha	Homo sapiens	129-133	
10547156-7	1999	Poly-L-lysine, but not poly-L-glutamic acid dose-dependently increased the urinary excretion of IL-1alpha.	Lysine	0-13	interleukin 1 alpha	Homo sapiens	96-105	
7590907-1	1995	The octapeptide Gly-Lys-Val-Leu-Lys-Lys-Arg-Arg (termed leukocorticotropin, LCT) corresponding to the ACTH-like sequence 81-88 of human pro-interleukin-1 alpha and its derivative Tyr-Gly-Lys-Val-Leu-Lys-Lys-Arg-Arg were synthesized.	Lysine	20-23	interleukin 1 alpha	Homo sapiens	136-159	
8346241-7	1993	To determine which lysine(s) are acylated, a series of synthetic peptides containing all lysines found in the IL-1 alpha N-terminal propiece were used in an in vitro myristoylation assay containing peptide, myristoyl-CoA, and monocyte lysate as enzyme source.	Lysine	89-96	interleukin 1 alpha	Homo sapiens	110-120	
31420217-5	2019	Mechanistically, SAM generation maintains a relatively high SAM:S-adenosylhomocysteine ratio to support histone H3 lysine 36 trimethylation for IL-1beta production.	Lysine	115-121	interleukin 1 alpha	Homo sapiens	144-152	
8346241-0	1993	The 31-kDa precursor of interleukin 1 alpha is myristoylated on specific lysines within the 16-kDa N-terminal propiece.	Lysine	73-80	interleukin 1 alpha	Homo sapiens	24-43	
8346241-4	1993	We report that the N terminus of the 31-kDa IL-1 alpha precursor is myristoylated on specific internal lysine residues.	Lysine	103-109	interleukin 1 alpha	Homo sapiens	44-54	
2198282-10	1990	We found that functional hIL-1 alpha had an absolute requirement for a basic residue (Arg, Lys, or His) at either position 15 or 16, and that Leu was preferred at position 40.	Lysine	91-94	interleukin 1 alpha	Homo sapiens	25-36