PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35182729-7 2022 Mechanistically, MAT2A mediates the production of S-adenosylmethionine (SAM), which upregulates ACSL3 by increasing the trimethylation of lysine-4 on histone H3 (H3K4me3) at the promoter area, resulting in ferroptosis resistance. Lysine 138-144 methionine adenosyltransferase 2A Homo sapiens 17-22