PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15895993-5 2005 Analysis of the NMR structure of the PITX2 homeodomain indicates that the lysine at position 50 makes contacts with two guanines on the antisense strand of the DNA, adjacent to the TAAT core DNA sequence, consistent with the structure of EnQ50K. Lysine 74-80 paired like homeodomain 2 Homo sapiens 37-42 29664630-5 2018 NMR methodology was employed for determining the dynamics of lysine side-chain amino groups via 15N relaxation measurements in the Lys50-class homeodomains from the Drosophila protein Bicoid and the human protein Pitx2. Lysine 61-67 paired like homeodomain 2 Homo sapiens 213-218 11301317-4 2001 The PITX2 homeodomain has a lysine at position 50, which has been shown to impart the bicoid-type (TAATCC) DNA binding specificity to other homeodomain proteins. Lysine 28-34 paired like homeodomain 2 Homo sapiens 4-9 11157981-3 2001 In this study we have identified a family of genes for enzymes responsible for hydroxylizing lysines in collagens as one group of likely cognate targets of PITX2 transcriptional regulation. Lysine 93-100 paired like homeodomain 2 Homo sapiens 156-161 15258251-7 2004 We found that lysine 204 of Galpha13 is important for interaction with the RGS domain of p115 or LARG and for the GTPase-activating protein activity of these proteins. Lysine 14-20 paired like homeodomain 2 Homo sapiens 75-78 15258251-9 2004 We conclude that lysine 204 of Galpha13 is important for interaction with RGS-RhoGEFs and is critically involved in the regulation of their activity. Lysine 17-23 paired like homeodomain 2 Homo sapiens 74-77