PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27824159-5 2016 D-2HG, but not L-2HG, increased the trimethylation of histone H3 lysine 4 of the promoter region of ZEB1, a master regulator of epithelial-mesenchymal transition (EMT), and increased the expression of the ZEB1 gene to directly induce EMT in colorectal cancer cells. Lysine 65-71 zinc finger E-box binding homeobox 1 Homo sapiens 100-104 24216980-5 2013 Following ZEB1 induction, acetylation of histone H4 and histone H3 on lysine 9 (H3K9) and 27 (H3K27) was decreased on ZEB1 binding sites on these genes as demonstrated by chromatin immunoprecipitation. Lysine 70-76 zinc finger E-box binding homeobox 1 Homo sapiens 10-14 26934322-7 2016 The downregulation of ZEB1 in fBMFs by resveratrol was mediated by epigenetic mechanisms, such as the upregulated expression of miR-200c and the enhancer of zeste homolog 2 (EZH2), as well as the trimethylated lysine 27 of histone H3 (H3K27me3). Lysine 210-216 zinc finger E-box binding homeobox 1 Homo sapiens 22-26 24216980-5 2013 Following ZEB1 induction, acetylation of histone H4 and histone H3 on lysine 9 (H3K9) and 27 (H3K27) was decreased on ZEB1 binding sites on these genes as demonstrated by chromatin immunoprecipitation. Lysine 70-76 zinc finger E-box binding homeobox 1 Homo sapiens 118-122 22384255-9 2012 This binding results in lysine acetylation of ZEB1 and a release of ZEB1 suppression on miR-200c/141 transcription. Lysine 24-30 zinc finger E-box binding homeobox 1 Homo sapiens 46-50 22384255-9 2012 This binding results in lysine acetylation of ZEB1 and a release of ZEB1 suppression on miR-200c/141 transcription. Lysine 24-30 zinc finger E-box binding homeobox 1 Homo sapiens 68-72 35286850-9 2022 In this study, we developed a hyaluronic acid (HA)/poly-L-lysine (PLL) layer-by-layer (LbL) self-assembly coating on beta-TCP (beta-tricalcium phosphate) scaffolds providing immobilization of modularized engineered sEVs (with c(RGDfC) surface functionalization and ZEB1 loading) to facilitate bone defect regeneration under DM conditions. Lysine 51-64 zinc finger E-box binding homeobox 1 Homo sapiens 265-269 33291558-9 2020 CONCLUSIONS: The results suggest that certain histone lysine methyltransferase/demethylase, such as MLL4, UTX, and EZH2, regulate the expression of EMT-TFs such as Slug, ZEB1, and Twist epigenetically, which may thereby influence cancer metastasis from the lung to the brain. Lysine 54-60 zinc finger E-box binding homeobox 1 Homo sapiens 170-174