PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32528730-6 2020 In contrast, activation of SIRT1 increased autophagy in chondrocytes by the deacetylation of lysine residues on crucial autophagy proteins (Beclin1, ATG5, ATG7, LC3). Lysine 93-99 autophagy related 5 Homo sapiens 149-153 9852036-14 1998 Mutagenic analyses suggested that this conjugation was formed via an isopeptide bond between the C-terminal glycine of hApg12 and Lys-130 of hApg5. Lysine 130-133 autophagy related 5 Homo sapiens 141-146 29634390-7 2018 Furthermore, we validate that this methylation at lysine 151 impairs the binding of ATG16L1 to the ATG12-ATG5 conjugate, leading to inhibition of autophagy and increased apoptosis in H/R-treated cardiomyocytes. Lysine 50-56 autophagy related 5 Homo sapiens 105-109 16963840-6 2007 We show that ATG7, ATG10 and ATP as an energy source are all essential for ATG12-ATG5 conjugation, and mutation of the specific lysine residue of ATG5 for ATG12 conjugation abrogates the reaction. Lysine 128-134 autophagy related 5 Homo sapiens 81-85 16963840-6 2007 We show that ATG7, ATG10 and ATP as an energy source are all essential for ATG12-ATG5 conjugation, and mutation of the specific lysine residue of ATG5 for ATG12 conjugation abrogates the reaction. Lysine 128-134 autophagy related 5 Homo sapiens 146-150 9852036-4 1998 The C-terminal glycine of a novel modifier protein, Apg12p, is conjugated to a lysine residue of Apg5p via an isopeptide bond. Lysine 79-85 autophagy related 5 Homo sapiens 97-102 24070470-4 2013 Sequential reactions by the E1 enzyme Atg7 and the E2 enzyme Atg10 conjugate Atg12 to the lysine residue in Atg5, and the resulting Atg12-Atg5 conjugate forms a complex with Atg16. Lysine 90-96 autophagy related 5 Homo sapiens 108-112 24070470-4 2013 Sequential reactions by the E1 enzyme Atg7 and the E2 enzyme Atg10 conjugate Atg12 to the lysine residue in Atg5, and the resulting Atg12-Atg5 conjugate forms a complex with Atg16. Lysine 90-96 autophagy related 5 Homo sapiens 138-142