PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31982938-5 2020 We now show that enhancement of brain ACE2 activity, a major effector of rRAS, by intraperitoneal administration of diminazene aceturate (DIZE), an established activator of ACE2, lowered hippocampal Abeta and restored cognition in mid-aged (13-14-month-old) symptomatic Tg2576 mice. diminazene aceturate 116-136 amyloid beta (A4) precursor protein Mus musculus 199-204 31982938-5 2020 We now show that enhancement of brain ACE2 activity, a major effector of rRAS, by intraperitoneal administration of diminazene aceturate (DIZE), an established activator of ACE2, lowered hippocampal Abeta and restored cognition in mid-aged (13-14-month-old) symptomatic Tg2576 mice. diminazene aceturate 138-142 amyloid beta (A4) precursor protein Mus musculus 199-204